| Effect of immunoadsorption on refractory idiopathic focal and segmental glomerulosclerosis. | |
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MedLine Citation:
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PMID: 17120233 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case of a young adult with refractory nephrotic syndrome due to focal segmental glomerulosclerosis is reported. Several treatments had been used without success including steroids, cyclophosphamide, cyclosporine A, tacrolimus, and mycophenolate mofetil. Immunoadsorption was performed as a last resort to manage the nephrotic syndrome, which led to a drastic urinary protein reduction. We review the literature supporting immunoadsorption in primary focal segmental glomerulosclerosis. |
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Authors:
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Christian Kuhn; Andrea Kuhn; Silke Markau; Uta Kästner; Bernd Osten |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of clinical apheresis Volume: 21 ISSN: 0733-2459 ISO Abbreviation: J Clin Apher Publication Date: 2006 Dec |
Date Detail:
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Created Date: 2006-12-26 Completed Date: 2007-03-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8216305 Medline TA: J Clin Apher Country: United States |
Other Details:
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Languages: eng Pagination: 266-70 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine II, University-Hospital Halle-Kröllwitz, Halle, Germany. christian.kuhn@medizin.uni-halle.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anemia, Megaloblastic / chemically induced Angiotensin II Type 1 Receptor Blockers / therapeutic use Angiotensin-Converting Enzyme Inhibitors / therapeutic use Azathioprine / adverse effects, therapeutic use Blood Proteins / chemistry Combined Modality Therapy Cyclophosphamide / therapeutic use Drug Resistance Glomerulosclerosis, Focal Segmental / complications, therapy* Humans Immunosorbent Techniques* Immunosuppressive Agents / adverse effects, therapeutic use Male Mycophenolic Acid / analogs & derivatives, therapeutic use Nephrotic Syndrome / etiology Plasmapheresis* Proteinuria / etiology Sepharose / chemistry Staphylococcal Protein A / chemistry Tacrolimus / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Angiotensin II Type 1 Receptor Blockers; 0/Angiotensin-Converting Enzyme Inhibitors; 0/Blood Proteins; 0/Immunosuppressive Agents; 0/Staphylococcal Protein A; 109581-93-3/Tacrolimus; 128794-94-5/mycophenolate mofetil; 24280-93-1/Mycophenolic Acid; 446-86-6/Azathioprine; 50-18-0/Cyclophosphamide; 9012-36-6/Sepharose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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