| Effect of hypnotic sedation during percutaneous transluminal coronary angioplasty on myocardial ischemia and cardiac sympathetic drive. | |
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MedLine Citation:
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PMID: 15081451 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Forty-six patients were randomized to receive drug (group 1) or hypnotic sedation (group 2) during percutaneous transluminal coronary angioplasty of the left anterior descending coronary artery. Intracoronary and standard electrocardiograms were continuously registered, and heart rate spectral variability was studied. Normalized units of low- and high-frequency components and the ratio of low to high frequency were measured during balloon inflations. The ST segment shifted at the first balloon inflation from 0.02 +/- 0.01 to 0.09 +/- 0.6 mm in group 1 and from 0.02 +/- 0.08 to 0.1 +/- 0.6 in group 2 mm (p <0.05). In group 1, the low-frequency band and the ratio of low to high frequency increased significantly during the first balloon inflation (from 59 +/- 10 to 75 +/- 10 normalized units and from 2.4 +/- 1.4 to 7.3 +/- 4.7, respectively; p <0.001). The increase of the ratio of low to high frequency was significantly related to ST shift (r = 0.706; p <0.01). In contrast, no significant variation of spectral parameters was found in group 2. The increase in cardiac sympathetic activity associated with balloon inflation and myocardial ischemia during percutaneous transluminal coronary angioplasty of the left anterior descending coronary artery was selectively eliminated by hypnosis but not by drug sedation. |
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Authors:
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Roberto Baglini; Marco Sesana; Cinzia Capuano; Tomaso Gnecchi-Ruscone; Limbruno Ugo; Gian Battista Danzi |
Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: The American journal of cardiology Volume: 93 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2004 Apr |
Date Detail:
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Created Date: 2004-04-14 Completed Date: 2004-05-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 1035-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Invasive Cardiology, Poliambulanza Hospital, Brescia, Italy. robagl@katamail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Transluminal, Percutaneous Coronary* Conscious Sedation / methods* Electrocardiography Female Heart / innervation* Heart Rate Humans Hypnosis* Male Middle Aged Myocardial Ischemia / therapy* Sympathetic Nervous System / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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