Document Detail

Effect of "living high-training low" on the cardiac functions at sea level.
MedLine Citation:
PMID:  9774204     Owner:  NLM     Status:  MEDLINE    
Living high-training low (LHTL), living at high altitude and training at sea level, is reported to be beneficial in enhancing physical performance. Effect of LHTL on cardiac function which is one of major determinants in performance, however, was not examined. To address this issue, 21 well-trained triathletes divided into control (n = 10, living and training at sea level) and LHTL group (living at 1980 m altitude > or = 12 hrs/day and training at sea level) were Doppler echocardiographically examined before and at the end of the two-week program. Heart rate and blood pressure did not change in both groups. At end of the training, left ventricular endsystolic diameter of LHTL group was smaller than that of controls (32 vs 34 mm, P < 0.05). Shortening fraction and ejection fraction in LHTL group increased by 9% and 17 %, respectively, P < 0.05. Preejection period/ejection time was more greatly reduced in LHTL group (P < 0.05). Stroke volume and cardiac output in LHTL increased. Diastolic function was not significantly affected by LHTL. These results suggest that LHTL produced an improvement of systolic function underlined by incremented left ventricular contractility, which might be associated with increased beta-adrenergic receptor or an improved myocardial energy utilization.
Y Liu; J M Steinacker; C Dehnert; E Menold; S Baur; W Lormes; M Lehmann
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of sports medicine     Volume:  19     ISSN:  0172-4622     ISO Abbreviation:  Int J Sports Med     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-12-17     Completed Date:  1998-12-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  380-4     Citation Subset:  IM; S    
Abt. Sport- und Leistungsmedizin, University of Ulm, Germany.
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MeSH Terms
Bicycling / education,  physiology*
Blood Pressure / physiology
Cardiac Output / physiology
Echocardiography, Doppler
Energy Metabolism / physiology
Heart / physiology*
Heart Rate / physiology
Heart Ventricles / metabolism,  ultrasonography
Myocardial Contraction / physiology
Myocardium / metabolism
Receptors, Adrenergic, beta / physiology
Running / education,  physiology*
Stroke Volume / physiology
Swimming / education,  physiology*
Ventricular Function, Left / physiology
Reg. No./Substance:
0/Receptors, Adrenergic, beta

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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