Document Detail

Effect of high-frequency jet ventilation on oxygenation during one-lung ventilation in patients undergoing thoracic aneurysm surgery.
MedLine Citation:
PMID:  16421668     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To evaluate the effect of high-frequency jet ventilation (HFJV) and continuous positive airway pressure (CPAP) on oxygenation and the shunt fraction (Qs/Qt) during one-lung ventilation (OLV). METHODS: Twenty-five patients who were undergoing resection of a descending aortic aneurysm were studied. Arterial oxygenation, Qs/Qt, and hemodynamics were evaluated just before the initiation of OLV (T1), 15 min after OLV (T2), and 15 min (T3) and 30 min (T4) after the application of HFJV or CPAP to the nondependent lung. RESULTS: There were no significant changes in the mean arterial blood pressure (MAP), heart rate (HR), central venous pressure (CVP), or mixed venous partial pressure of oxygen throughout this study. The arterial partial pressure of oxygen (Pa(O2)) values after the application of HFJV or CPAP increased significantly, from 173.8 +/- 39.6 mmHg (T2) to 344.1 +/- 87.9 mmHg (T3) and 359.9 +/- 82.4 mmHg (T4) in the HFJV group (P < 0.05), and from 153 +/- 38.5 mmHg (T2) to 243 +/- 48.5 mmHg (T3) and 249.7 +/- 55.0 mmHg (T4) in the CPAP group (P < 0.05). The shunt fraction decreased significantly after the initiation of HFJV or CPAP, from 38.7% +/- 8.9% (T2) to 27.0% +/- 8.0% (T3) and 25.9% +/- 8.7% (T4) in the HFJV group (P < 0.05), and from 44.6% +/- 8.6% (T2) to 34.3% +/- 10.2% (T3) and 32.6% +/- 8.5% (T4) in the CPAP group (P < 0.05). The arterial saturation of oxygen (Sa(O) (2)) increased significantly after the application of either HFJV or CPAP (P < 0.05). CONCLUSIONS: Both HFJV and CPAP can improve oxygenation during OLV.
Kazuo Abe; Junko Oka; Hibiki Takahashi; Toshihiro Funatsu; Hirotsugu Fukuda; Yuji Miyamoto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of anesthesia     Volume:  20     ISSN:  0913-8668     ISO Abbreviation:  J Anesth     Publication Date:  2006  
Date Detail:
Created Date:  2006-01-19     Completed Date:  2006-03-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8905667     Medline TA:  J Anesth     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1-5     Citation Subset:  IM    
Department of Anesthesiology, Sakurabashi Watanabe Hospital, 2-4-32 Umeda, Kita-ku, Osaka 530-0001, Japan.
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MeSH Terms
Aortic Aneurysm, Thoracic / surgery*
Continuous Positive Airway Pressure
High-Frequency Jet Ventilation*
Lung / physiology
Middle Aged
Oxygen / metabolism*
Reg. No./Substance:

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