| Effect of high-frequency hearing loss on compound action potentials recorded from the intracranial portion of the human eighth nerve. | |
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MedLine Citation:
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PMID: 1752798 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Compound action potentials (CAP) were recorded from the exposed intracranial portion of the eighth nerve to stimulation with click sounds in patients with sensorineural high-frequency hearing loss who underwent microvascular decompression (MVD) operations to treat trigeminal neuralgia (TN). In patients with normal hearing the CAP recorded in that way is characterized by a negative peak, preceded by a small positivity and followed by a positivity and sometimes a second negative peak. In patients with high-frequency hearing loss the CAP also usually had an initial sharp negative peak in response to clicks of high intensity (105 to 110 dB Pe SPL), similar to findings in patients with normal hearing, but in patients with high-frequency hearing loss the initial negative peak was often followed by a slow negative deflection. The latency of the initial negative peak in the CAP in patients with high-frequency hearing loss was longer than the latency of this peak in patients with normal hearing, but the difference in latencies of this peak to condensation and rarefaction clicks was small. When the stimulus intensity was lowered the amplitude of the initial peak decreased, and the CAP became dominated by a broad negative peak with a latency of 6 to 8 ms. In 11 of 15 patients with severe high-frequency hearing loss, a series of quasi-periodic waves was superimposed on the CAP. The frequency of these waves varied between 500 and 1200 Hz, and the waves could be detected between 6 and 16 ms after presentation of the click stimulus. These waves were usually present in the response to stimuli in the intensity range from 75 to 110 dB Pe SPL. Only 4 of 17 patients with normal hearing had similar waves. |
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Authors:
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A R Møller; H D Jho |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Hearing research Volume: 55 ISSN: 0378-5955 ISO Abbreviation: Hear. Res. Publication Date: 1991 Sep |
Date Detail:
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Created Date: 1992-01-27 Completed Date: 1992-01-27 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7900445 Medline TA: Hear Res Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 9-23 Citation Subset: IM |
Affiliation:
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Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pennsylvania. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acoustic Stimulation Action Potentials Evoked Potentials, Auditory, Brain Stem Hearing Loss, High-Frequency / complications, physiopathology* Hearing Loss, Sensorineural / complications, physiopathology Humans Trigeminal Neuralgia / complications, surgery Vestibulocochlear Nerve / physiopathology |
| Grant Support | |
ID/Acronym/Agency:
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R01-DC00272/DC/NIDCD NIH HHS; R01-NS21378/NS/NINDS NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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