Document Detail


Effect of a herbal yeast food supplement and long-distance running on immunological parameters.
MedLine Citation:
PMID:  2265308     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of a food supplement on immunological parameters of 16 long-distance runners was tested in a randomized, double-blind and placebo-controlled trial. The supplement comprised plasmolysed herbal yeast, malt, honey, and orange juice. No statistically significant differences between the two groups regarding the following variables were detected at three sessions at rest and immediately after a 21 km run: total and differential white blood cell counts, numbers of B- and T-cells and T-subpopulations, concanavalin-A-induced lymphocyte proliferation, serum levels of immunoglobulins, neopterin, IL-2 receptors, beta 2-microglobulin, complement factor b, c4 and c3c, and c1-inactivator. These findings suggest that the effects of the tested food supplement on these parameters are negligible with respect to improvements in the immunological status of long-distance runners. The changes observed immediately after the run had a transient character. In both groups, however, low lymphocyte counts, IgG subclass 2 levels and c1-inactivator levels were noted at rest, which indicate that the immune status of endurance athletes may be affected by training.
Authors:
F K Gmünder; P W Joller; H I Joller-Jemelka; B Bechler; M Cogoli; W H Ziegler; J Müller; R E Aeppli; A Cogoli
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  British journal of sports medicine     Volume:  24     ISSN:  0306-3674     ISO Abbreviation:  Br J Sports Med     Publication Date:  1990 Jun 
Date Detail:
Created Date:  1991-02-11     Completed Date:  1991-02-11     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0432520     Medline TA:  Br J Sports Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  103-12     Citation Subset:  IM; S    
Affiliation:
Institute of Biotechnology, Swiss Federal Institute of Technology, Zurich.
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MeSH Terms
Descriptor/Qualifier:
Adult
Angiosperms*
Antibody Formation* / physiology
Double-Blind Method
Exercise* / physiology
Female
Humans
Immunity, Cellular* / physiology
Male
Physical Endurance
Running*
Yeast, Dried / administration & dosage
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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