Document Detail


Effect of hepatoprotective ayurvedic drugs on lysosomal enzymes during hepatic injury induced by single dose of CCl4.
MedLine Citation:
PMID:  7927526     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Effects of single doses of kumari asav, kumari kalp, arogyavardhini and tamra bhasma on lysosomal enzymes (acid phosphatase and beta-glucuronidase) of rat liver and kidney were studied during hepatitis induced by single 0.3 ml/kg body wt dose of CCl4. Histologically all the drugs showed significant hepatoprotection. While acid phosphatase activities of liver and kidney were suppressed, activities of beta-glucuronidase were enhanced by these drugs. The results indicate that acid phosphatase and beta-glucuronidase behave differently, although they are lysosomal in nature.
Authors:
R Kanase; S Patil; A Kanase
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Indian journal of experimental biology     Volume:  32     ISSN:  0019-5189     ISO Abbreviation:  Indian J. Exp. Biol.     Publication Date:  1994 May 
Date Detail:
Created Date:  1994-11-07     Completed Date:  1994-11-07     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0233411     Medline TA:  Indian J Exp Biol     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  328-32     Citation Subset:  IM    
Affiliation:
Department of Zoology, Shivaji University, Kolhapur, India.
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MeSH Terms
Descriptor/Qualifier:
Animals
Carbon Tetrachloride Poisoning / prevention & control*
Drug-Induced Liver Injury / enzymology,  prevention & control*
Lysosomes / drug effects*,  enzymology
Male
Medicine, Ayurvedic*
Rats
Rats, Inbred Strains

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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