Document Detail

Effect of hemodynamic conditions on sonographic measurements of peak systolic velocity and arterial diameter in patients with peripheral arterial stenosis.
MedLine Citation:
PMID:  10679696     Owner:  NLM     Status:  MEDLINE    
PURPOSE: We measured changes in peak systolic velocity ratio and sonogaphic vascular diameter during different hemodynamic conditions in patients with femoral or iliac artery stenosis. METHODS: In 35 patients with isolated femoral or iliac artery stenosis, prestenotic and intrastenotic peak systolic velocity and inner vascular diameter were calculated using color Doppler sonography and gray-scale sonography, respectively. The measurements were performed with the patient at rest (baseline), after leg exercise, and again after oral administration of 10 mg of the vasodilator nifedipine. RESULTS: The mean prestenotic and intrastenotic peak systolic velocity and the peak systolic velocity ratio (intrastenotic/prestenotic peak systolic velocity) were 70 +/- 31 cm/second, 360 +/- 130 cm/second, and 6.5 +/- 3.6 at baseline; 78 +/- 37 cm/second, 404 +/- 171 cm/second, and 6.6 +/- 4.2 after leg exercise; and 71 +/- 30 cm/second, 353 +/- 109 cm/second, and 5.9 +/- 3.2 after nifedipine administration. The mean prestenotic and intrastenotic diameter and percentage of diameter reduction were 5.9 +/- 3.2 mm, 2.3 +/- 1.1 mm, and 59 +/- 13% at baseline; 4.8 +/- 2.4 mm, 2.0 +/- 1.3 mm, and 62 +/- 13% after leg exercise; and 5.9 +/- 2.9 mm, 2.5 +/- 1.0 mm, and 54 +/- 14% after nifedipine administration. Only the difference in intrastenotic diameter after leg exercise was significantly different from baseline. CONCLUSIONS: The peak systolic velocity ratio in peripheral arterial stenosis seems to be relatively independent of the hemodynamic conditions and cannot be used for investigations of vasomotion of stenotic arterial segments during different hemodynamic conditions.
K Kröger; K Massalha; C Buss; G Rudofsky
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  28     ISSN:  0091-2751     ISO Abbreviation:  J Clin Ultrasound     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-03-27     Completed Date:  2000-03-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  109-14     Citation Subset:  IM    
Copyright Information:
Copyright 2000 John Wiley & Sons, Inc.
Department of Angiology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany.
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MeSH Terms
Administration, Oral
Arterial Occlusive Diseases / physiopathology,  ultrasonography*
Blood Flow Velocity
Exercise Test
Femoral Artery / drug effects,  physiopathology,  ultrasonography*
Iliac Artery / drug effects,  physiopathology,  ultrasonography*
Middle Aged
Nifedipine / administration & dosage,  diagnostic use
Ultrasonography, Doppler, Color
Vasodilation / drug effects
Vasodilator Agents / administration & dosage,  diagnostic use
Reg. No./Substance:
0/Vasodilator Agents; 21829-25-4/Nifedipine

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