Document Detail

Effect of heart rate on the end-systolic wall stress-mean velocity of circumferential fiber shortening relation.
MedLine Citation:
PMID:  3249269     Owner:  NLM     Status:  MEDLINE    
The correlation of left ventricular end-systolic wall stress (ESS) with the mean velocity of fiber shortening (mVcf) is an index of the myocardial contractile state, independent of the ventricular loading conditions (afterload). However, there have been few reported estimates of the effect of changes in the heart rate on the ESS-mVcf relationship. In the present study, 25 subjects with histories of Kawasaki disease (mucocutaneous lymph node syndrome: MCLS) were evaluated for the effects of changes in heart rate, afterload and preload, on the ESS-mVcf relationship. The latter was independent of afterload. After atrial pacing, ESS decreased and mVcf increased, both significantly, compared to those of subjects at rest. The change of the ESS-mVcf relationship induced by atrial pacing approximately paralleled the mean regression line obtained in the resting state. However, the shift induced by preload was not parallel to the mean regression line for the resting population. These data suggest that the ESS-mVcf relationship is independent of any change in heart rate, and that it may depend on preload.
K Watanabe; K Kishida; N Haneda; N Horino; T Nishio; C Mori
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cardiology     Volume:  18     ISSN:  0914-5087     ISO Abbreviation:  J Cardiol     Publication Date:  1988 Jun 
Date Detail:
Created Date:  1989-07-05     Completed Date:  1989-07-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8804703     Medline TA:  J Cardiol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  451-6     Citation Subset:  IM    
Department of Pediatrics, Shimane Medical University.
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MeSH Terms
Child, Preschool
Heart Catheterization
Heart Rate*
Heart Ventricles / physiopathology
Mucocutaneous Lymph Node Syndrome / physiopathology*
Myocardial Contraction*
Regression Analysis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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