Document Detail

Effect of haemoglobin levels on cerebral infarct subtypes at high altitude.
MedLine Citation:
PMID:  9487412     Owner:  NLM     Status:  MEDLINE    
In a prospective observational study of haemoglobin (Hb) values of Saudi nationals presenting to Assir Central Hospital, Abha (altitude 2500m) with first-ever acute cerebral infarction, the mean Hb concentration and the proportion of patients with subcortical infarct (SCI) who had Hb values of 14.5g/dl or greater (high normal Hb group), were compared with those of cortical infarct (COI) patients and controls. Thirty-six (22.8%) of 158 patients had SCI and 122 had COI. The mean Hb of SCI patients was 15.2g/dl compared with 14.7g/dl for age and sex matched controls (p = 0.16; NS) and 14.5 g/dl for COI patients (p = 0.10; NS). However, a significantly greater proportion of SCI patients (72%) had high normal Hb values compared with 51% of COI patients (p = 0.02). The difference between the proportion of SCI patients (72%) who had high normal Hb and that of controls (64%) was not significant (p = 0.58). There was a small but significantly increased risk of experiencing SCI as against COI if a patient's Hb value was in the high normal range (odds ratio 2.5; 95% Confidence Interval 1.1 to 5.7 for combined male and female data and 3.8; 95% CI, 1.02 to 13.77 for male patients).
A C Longe; B al-Ghamdi
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  East African medical journal     Volume:  74     ISSN:  0012-835X     ISO Abbreviation:  East Afr Med J     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1998-03-13     Completed Date:  1998-03-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372766     Medline TA:  East Afr Med J     Country:  KENYA    
Other Details:
Languages:  eng     Pagination:  487-90     Citation Subset:  IM    
Department of Medicine, College of Medicine, King Saud University, Abha, Saudi Arabia.
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MeSH Terms
Acute Disease
Aged, 80 and over
Case-Control Studies
Cerebral Infarction / blood*,  classification,  etiology*
Hemoglobins / analysis*
Middle Aged
Odds Ratio
Prospective Studies
Risk Factors
Saudi Arabia
Reg. No./Substance:

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