Document Detail


Effect of gossypol on boar spermatozoa in vitro.
MedLine Citation:
PMID:  7271366     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gossypol, the active component in cottonseed oil, inhibits spermatogenesis in many mammals. Gossypol enhanced respiration and abolished forward motility of boar spermatozoa. The effective concentration was 10(-5) M, similar to that reported in its uncoupling of oxidative phosphorylation in rat liver mitochondria. Its antifertility effect may be a combination of the effect on the developing spermatids as well as that on spermatozoal motility.
Authors:
W W Tso; C S Lee
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of andrology     Volume:  7     ISSN:  0148-5016     ISO Abbreviation:  Arch. Androl.     Publication Date:  1981 Aug 
Date Detail:
Created Date:  1981-10-29     Completed Date:  1981-10-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806755     Medline TA:  Arch Androl     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  85-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Gossypol / pharmacology*
Male
Oxygen Consumption / drug effects
Sperm Motility / drug effects
Spermatozoa / drug effects*
Swine
Chemical
Reg. No./Substance:
303-45-7/Gossypol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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