| Effect of gonadotrophin priming on in-vitro maturation of oocytes collected from women at risk of OHSS. | |
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MedLine Citation:
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PMID: 16984762 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study examined the effects of human menopausal gonadotrophin (HMG) or human chorionic gonadotrophin (HCG) priming on cumulus-oocyte complex (COC) morphology, oocyte maturation and embryo development in patients undergoing in-vitro maturation (IVM) cycles. The patients were primed with nothing (group 1), low-dose HMG (group 2) or 10,000 IU HCG (group 3) before oocyte retrieval. COC with dispersed cumulus cell appearance was only observed in group 3. In addition, 11% of metaphase II stage oocytes at the time of retrieval were collected from group 3. Oocyte maturation in vitro in group 3 was faster than that in groups 1 and 2. The blastocyst development rate of residual embryos after embryo transfer in group 3 was significantly higher than that of groups 1 and 2 (P < 0.05). These results suggest that HCG priming may stimulate the COC, promote oocyte maturation, and improve developmental competence in IVM cycles. |
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Authors:
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Weon-Young Son; San-Hyun Yoon; Jin-Ho Lim |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Reproductive biomedicine online Volume: 13 ISSN: 1472-6483 ISO Abbreviation: Reprod. Biomed. Online Publication Date: 2006 Sep |
Date Detail:
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Created Date: 2006-09-20 Completed Date: 2006-12-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101122473 Medline TA: Reprod Biomed Online Country: England |
Other Details:
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Languages: eng Pagination: 340-8 Citation Subset: IM |
Affiliation:
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Maria Infertility Hospital, Seoul 130-812, Korea. weon-young.son@muhc.mcgill.ca |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chorionic Gonadotropin / therapeutic use* Embryo Transfer Female Fertilization in Vitro Humans Menotropins / therapeutic use* Oocyte Donation / methods* Oocytes / physiology* Ovarian Hyperstimulation Syndrome / prevention & control* Retrospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Chorionic Gonadotropin; 61489-71-2/Menotropins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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