| Effect of glycerol on pressure difference between perilymph and endolymph. | |
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MedLine Citation:
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PMID: 2386035 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The pressure difference between the perilymph and the endolymph following administration of 50% glycerol (12 ml/kg) was studied in guinea pigs. The perilymphatic and endolymphatic pressures were measured simultaneously with two sets of a servo-nulling system. Glycerol was administered for about one minute via a gastrocatheter. Both the perilymphatic and endolymphatic pressures began to decrease about 5 min after the administration of glycerol, and thereafter the decrease continued for about one hour with no significant difference between the two pressures. We concluded from the results that the glycerol-induced pressure difference between the perilymph and the endolymph, if present, is only a very small one, although a collapse of the scala media after glycerol intake was reported in guinea pigs and chinchillas. |
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Authors:
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T Takeda; S Takeuchi; H Saito |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta oto-laryngologica Volume: 110 ISSN: 0001-6489 ISO Abbreviation: Acta Otolaryngol. Publication Date: 1990 Jul-Aug |
Date Detail:
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Created Date: 1990-09-20 Completed Date: 1990-09-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370354 Medline TA: Acta Otolaryngol Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 68-72 Citation Subset: IM |
Affiliation:
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Department of Otolaryngology, Kochi Medical School, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Endolymph / drug effects* Glycerol / administration & dosage, pharmacology* Guinea Pigs Labyrinthine Fluids / drug effects* Perilymph / drug effects* Pressure |
| Chemical | |
Reg. No./Substance:
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56-81-5/Glycerol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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