| Effect of glycerol, mannitol, and lasix on cerebrospinal fluid pressure in the acute period of a stroke | |
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MedLine Citation:
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PMID: 6797162 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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On giving a dose of glycerol (orally), mannitol or lasix (intravenously) to patients with a cerebral stroke in the acute period the cerebrospinal fluid (CSF) pressure in them dropped, on the average, by 70-80%, 65-70%, and 25-30%, respectively. However in 6.5 to 7.5 hours it rose again and the after-effect phenomenon appeared. The effects of the drugs having been over, the CSF pressure was found to exceed the initial level by 50-60% after the glycerol intake; by 75 to 80% after the mannitol, an by 4 to 6% after the lasix injections. When glycerol, mannitol, and lasix were given rectally the CSF pressure dropped, respectively, by 35-45%, 35-40%, and 20-25% below the initial level, and did not rise throughout the whole period of the observation. |
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Authors:
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N S Misiuk; V I Kurgaev |
Publication Detail:
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Type: Comparative Study; English Abstract; Journal Article |
Journal Detail:
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Title: Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) Volume: 81 ISSN: 0044-4588 ISO Abbreviation: Zh Nevropatol Psikhiatr Im S S Korsakova Publication Date: 1981 |
Date Detail:
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Created Date: 1982-02-12 Completed Date: 1982-02-12 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8710066 Medline TA: Zh Nevropatol Psikhiatr Im S S Korsakova Country: USSR |
Other Details:
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Languages: rus Pagination: 1149-52 Citation Subset: IM |
Vernacular Title:
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O vliianii glitserina, mannitola i laziksa na likvornoe davlenie v ostrom periode pozgovogo insul'ta. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Brain Edema / prevention & control* Brain Ischemia / cerebrospinal fluid, drug therapy* Cerebral Hemorrhage / cerebrospinal fluid, drug therapy* Female Furosemide / therapeutic use* Glycerol / therapeutic use* Humans Intracranial Pressure Male Mannitol / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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54-31-9/Furosemide; 56-81-5/Glycerol; 69-65-8/Mannitol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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