| Effect of glutamine supplementation on neutrophil function in male judoists. | |
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MedLine Citation:
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PMID: 23348981 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Glutamine is an important amino acid for immune function. Though high intensity and prolonged exercise decreases plasma glutamine concentration and causes immune suppression, the relationship between neutrophil functions and glutamine has not yet been found. The purpose of this study was to investigate the impacts of glutamine supplementation on neutrophil function. Twenty-six male university judoists were recruited. Subjects were classified into glutamine and control groups. The glutamine group ingested 3000 mg of glutamine per day and the control group ingested placebo for 2 weeks. Examinations were performed at the start of preunified loading exercise (pre-ULE), then 1 and 2 weeks after ULE (post-ULE). Reactive oxygen species (ROS) production, phagocytic activity, serum opsonic activity and serum myogenic enzymes were measured. Differences between the levels obtained in pre-ULE and post-ULE for the two groups were compared. In the glutamine group, ROS production activity increased 1 week after ULE, whereas it was not observed in the control group (P < 0.001). Though myogenic enzymes increased significantly after ULE (P < 0.001), the glutamine group remained unchanged by supplementation during ULE. Glutamine supplementation has prevented excessive muscle damage and suppression of neutrophil function, especially in ROS production activity, even during an intensive training period. Copyright © 2013 John Wiley & Sons, Ltd. |
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Authors:
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Eiji Sasaki; Takashi Umeda; Ippei Takahashi; Kojima Arata; Yousuke Yamamoto; Masaru Tanabe; Kazuyuki Oyamada; Erika Hashizume; Shigeyuki Nakaji |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-24 |
Journal Detail:
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Title: Luminescence : the journal of biological and chemical luminescence Volume: - ISSN: 1522-7243 ISO Abbreviation: Luminescence Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100889025 Medline TA: Luminescence Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2013 John Wiley & Sons, Ltd. |
Affiliation:
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Department of Social Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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