Document Detail

Effect of glucose utilization inhibitor isolated from the serum and urine of patients with chronic renal failure on the free fatty acid metabolism in rat kidney cortex slices.
MedLine Citation:
PMID:  131346     Owner:  NLM     Status:  MEDLINE    
The authors studied interference by the inhibitor of glucose utilization with free fatty acid (FFA) metabolism in rat kidney cortex slices. They found that FFA uptake by the kidneys, their incorporation into triglycerides (TG) and oxidation to 14CO2 were lower when the inhibitor was present in the incubation medium. The findings show that the inhibitor, as well as inhibiting glucose utilization in various tissues, interferes directly with fat metabolism.
V Chorváthová; R Dzúrik; R Ondreicka; L Ozdín; R Nemec; J Cerveń
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Physiologia Bohemoslovaca     Volume:  25     ISSN:  0369-9463     ISO Abbreviation:  Physiol Bohemoslov     Publication Date:  1976  
Date Detail:
Created Date:  1976-07-06     Completed Date:  1976-07-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0175317     Medline TA:  Physiol Bohemoslov     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  123-7     Citation Subset:  IM    
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MeSH Terms
Carbohydrate Metabolism
Fatty Acids, Nonesterified / metabolism*
Glucose / antagonists & inhibitors*
Kidney Cortex / metabolism*
Kidney Failure, Chronic / metabolism*
Reg. No./Substance:
0/Fatty Acids, Nonesterified; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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