Document Detail

Effect of gestational length on albumin content of meconium.
MedLine Citation:
PMID:  1275547     Owner:  NLM     Status:  MEDLINE    
During a screening programme for the detection of CF using the meconium albumin technique, the overall false-positive rate was found to be approximately 1%. When the gestational age of the infants was taken into account the false-positive rate was found to be significantly higher in preterm (8%) as compared to term infants (0.55%). This was due largely but not solely to the presence of occult blood. Possible explanations for these findings are discussed and attention drawn to the limitation of meconium albumin content as a screening technique for CF in preterm infants.
A D Griffiths; F E Bull; P Dykes
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  51     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1976 Apr 
Date Detail:
Created Date:  1976-08-02     Completed Date:  1976-08-02     Revised Date:  2010-09-07    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  321-3     Citation Subset:  IM    
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MeSH Terms
Albumins / analysis*
Cystic Fibrosis / diagnosis
False Positive Reactions
Gestational Age*
Infant, Newborn
Infant, Premature
Meconium / analysis*
Occult Blood
Reg. No./Substance:

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