Document Detail


Effect of germinal matrix hemorrhage on terminal vein position and patency.
MedLine Citation:
PMID:  8577549     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: Pathologic studies have suggested that periventricular intraparenchymal hemorrhages (IPH) occur as the result of compression and occlusion of terminal veins (TV) by germinal matrix hemorrhages (GMH). This study used color Doppler ultrasound techniques to test this hypothesis in vivo. MATERIALS AND METHODS: Twenty-four infants with 32 intracranial hemorrhages (20 GMH, 12 GMH/IPH) were evaluated during routine sonography with color and duplex Doppler ultrasound using an ACUSON 128 XP unit with 7-MHz linear and vector transducers. Maximum transverse dimension was obtained for each GMH. On coronal color Doppler ultrasound images, TVs were evaluated for displacement, presence of flow, and time average velocity (TAV). RESULTS: Abnormalities of the TV were common with ipsilateral GMH. Of 48 terminal veins evaluated, no flow was identified in 13 (27 %), and flow in a displaced vein was seen in eight (17 %). TV abnormality occurred more frequently with GMH/IPH (90 %) than with GMH alone (52 %), and complete occlusion of the TV was more common in GMH/IPH (82 %) than in GMH alone (16 %, p < 0.002). GMH size correlated with increasing TV abnormality. Mean transverse GMH dimensions with unaffected TV, displaced TV, and occluded TV were 8.2 +/- 1 mm, 10.3 +/- 1 mm, and 12.6 +/- 1 mm, respectively (p = 0.008). A small but significant trend was observed between maximum GMH dimension and decreasing TV velocities (r = - 0.5, p < 0.01). CONCLUSIONS: Obstruction of terminal veins by germinal matrix hemorrhage may play an important role in the pathogenesis of periventricular white matter hemorrhage.
Authors:
G A Taylor
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric radiology     Volume:  25 Suppl 1     ISSN:  0301-0449     ISO Abbreviation:  Pediatr Radiol     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1996-03-11     Completed Date:  1996-03-11     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  0365332     Medline TA:  Pediatr Radiol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  S37-40     Citation Subset:  IM    
Affiliation:
Department of Radiology and Pediatrics The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
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MeSH Terms
Descriptor/Qualifier:
Cerebral Hemorrhage / complications,  physiopathology,  ultrasonography*
Cerebral Veins / physiopathology,  ultrasonography*
Cerebrovascular Circulation
Constriction, Pathologic / etiology,  ultrasonography
Humans
Infant, Newborn
Infant, Premature, Diseases / ultrasonography*
Ultrasonography, Doppler, Color
Ultrasonography, Doppler, Transcranial
Vascular Patency

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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