| Effect of gamma, ethylene oxide, electron beam, and plasma sterilization on the behaviour of SR-PLLA fibres in vitro. | |
| | |
MedLine Citation:
|
PMID: 12555899 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The aim of this study was to evaluate the effect of various sterilization processes on the physical and mechanical properties of self-reinforced bioabsorbable fibres made out of polylactide (PLLA). The samples were sterilized using plasma, ethylene oxide (one and two cycles), gamma (25 kGy at room temperature, 25 kGy in dry ice, and 2 x 25 kGy at room temperature), and electron beam (15, 25, and 55 kGy) sterilization. The intrinsic viscosity, crystallinity, and mechanical properties (modulus of elasticity, yield strength, and ultimate tensile strength) were tested before and immediately after each sterilization treatment, as well as up to 30 weeks in vitro. Compared with unsterilized fibres, the intrinsic viscosity was markedly decreased after radiation sterilization (gamma and electron beam) and the loss in mechanical properties was accelerated during in vitro degradation. Plasma and ethylene oxide (one and two cycles) did not markedly alter the properties of the samples after sterilization or during in vitro degradation. These data are important for determining the effect of various sterilization processes on the physical and mechanical properties of polylactide-based materials and can be used to predict how fast degradation of the mechanical properties of the self-reinforced PLLA will occur. They can also be used to tailor the degradation kinetics to optimize implant design. |
| | |
Authors:
|
Juha-Pekka Nuutinen; Claude Clerc; Tuija Virta; Pertti Törmälä |
Related Documents
:
|
11460469 - Structure and properties of clots from fibrinogen bicêtre ii (gamma 308 asn-->lys). in... 15695239 - Are all photon radiations similar in large absorbers?--a comparison of electron spectra. 17810509 - Electrons and protons accelerated in mercury's magnetic field. 16090799 - Improved measurement of the cabibbo-kobayashi-maskawa angle alpha using b0(b) --> rho+r... 641579 - Comparing the performance of two gamma cameras under high counting rates: principles an... 16471939 - Thermodynamic confinement and alpha-helix persistence length in poly(gamma-benzyl-l-glu... 9836629 - X-ray crystal structure of the fe-only hydrogenase (cpi) from clostridium pasteurianum ... 6678099 - Assembly and reliability of an x-ray microanalyser system with a possibility for indepe... 19965389 - Universality in three- and four-body bound states of ultracold atoms. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of biomaterials science. Polymer edition Volume: 13 ISSN: 0920-5063 ISO Abbreviation: J Biomater Sci Polym Ed Publication Date: 2002 |
Date Detail:
|
Created Date: 2003-01-30 Completed Date: 2003-07-22 Revised Date: 2009-11-19 |
Medline Journal Info:
|
Nlm Unique ID: 9007393 Medline TA: J Biomater Sci Polym Ed Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 1325-36 Citation Subset: IM |
Affiliation:
|
Institute of Biomaterials, Tampere University of Technology, PO Box 589, FIN-33101, Tampere, Finland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Absorbable Implants* Beta Particles Biocompatible Materials* Calorimetry, Differential Scanning Elasticity Electrons* Ethylene Oxide* Gamma Rays* Humans Materials Testing / methods Polyesters / chemistry* Sterilization / methods* Tensile Strength Viscosity |
| Chemical | |
Reg. No./Substance:
|
0/Biocompatible Materials; 0/Polyesters; 26969-66-4/poly(lactide); 75-21-8/Ethylene Oxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Mechanical properties and in vitro degradation of bioresorbable knitted stents.
Next Document: Phase separation and physical properties of PEO-containing poly(ether ester amide)s.