Document Detail


Effect of frusemide on bodyweight loss and recovery in racing Standardbreds.
MedLine Citation:
PMID:  12405679     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study was conducted to compare bodyweight (bwt) loss and recovery in Standardbred horses receiving frusemide compared to controls. Thirty Standardbred horses from 7 training stables that were racing at the Red Mile in Lexington, Kentucky, during the spring 2001 pari-mutuel meeting were studied. Fourteen horses (FRU) received frusemide (250 mg/horse i.v.) 4 h prior to racing, while 16 horses (NFRU) did not received frusemide. Horses were weighed on the morning of race day, prior to warm-up, after racing and the next day. Changes in bwt were calculated as percentage increase or decrease from initial bwt. Prior to warm-up, FRU horses had a mean bwt reduction of 1.30 +/- 0.63%, (P<0.01), compared to a 0.19 +/- 0.63% increase for the NFRU horses. FRU horses had a greater (P<0.03) postrace bwt loss (3.55 +/- 0.55%) than the NFRU horses (2.71 +/- 0.66%). On the morning after racing, bwt was still below initial values by 0.90 +/- 0.55 and 1.24 +/- 0.35% for the FRU and the NFRU horses, respectively. While frusemide administration increased the postrace weight loss in racing Standardbreds, it did not affect short-term bwt recovery. Further research is required into management strategies required to allow horses to replenish fluids and electrolytes safely following strenuous exercise.
Authors:
R J Coleman; A C St Lawrence; L M Lawrence; A M Roberts
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Equine veterinary journal. Supplement     Volume:  -     ISSN:  -     ISO Abbreviation:  Equine Vet J Suppl     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-10-30     Completed Date:  2003-02-26     Revised Date:  2007-05-18    
Medline Journal Info:
Nlm Unique ID:  9614088     Medline TA:  Equine Vet J Suppl     Country:  England    
Other Details:
Languages:  eng     Pagination:  165-7     Citation Subset:  IM    
Affiliation:
Department of Animal Sciences, University of Kentucky, Lexington 40546-0215, USA.
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MeSH Terms
Descriptor/Qualifier:
Acid-Base Equilibrium
Animals
Body Weight / drug effects*
Dehydration / etiology,  prevention & control,  veterinary
Diuretics / pharmacology*
Female
Furosemide / pharmacology*
Horse Diseases / etiology,  prevention & control
Horses / physiology*
Male
Physical Conditioning, Animal / physiology*
Running
Sports
Weight Loss
Chemical
Reg. No./Substance:
0/Diuretics; 54-31-9/Furosemide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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