Document Detail

Effect of formic acid on performance, digestibility, intestinal histomorphology and plasma metabolite levels of broiler chickens.
MedLine Citation:
PMID:  16546797     Owner:  NLM     Status:  MEDLINE    
1. The effect of dietary formic acid on performance, digestibility, intestinal histomorphology and plasma metabolite levels of broiler chickens was studied. 2. An experiment with 120 Ross male broiler chickens was conducted from 1 to 42 d of age at the laboratory. There were 4 treatment groups: control (C), 10 mg/kg feed avilamycin (AV) and formic acid at two concentrations, 5 and 10 g/kg feed (FA5 and FA10, respectively). 3. No differences in weight gain, feed intake or feed conversion ratio were observed in male broiler chickens fed on the different diets. 4. An effect of the additives on ileal dry matter (DM) digestibility at 42 d of age was detected with the finisher diets; AV and 10 g/kg of feed formic acid slightly improved ileal DM digestibility compared to the other treatment groups. 5. Jejunum pH was not affected when 5 or 10 g/kg formic acid was added, and the results do not clearly show a positive effect of formic acid on the intestinal histomorphology. 6. No differences were noticed for blood metabolites in the different diets, and the levels of calcium and phosphorus in the plasma were not altered by formic acid addition. 7. In conclusion, when using broiler chickens under conditions of good hygiene, dietary formic acid did not have a clear positive effect on performance, intestinal histomorphology or plasma metabolite levels; however, there was a slight positive effect on the ileal digestibility of nutrients.
F Hernández; V García; J Madrid; J Orengo; P Catalá; M D Megías
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  British poultry science     Volume:  47     ISSN:  0007-1668     ISO Abbreviation:  Br. Poult. Sci.     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-03-20     Completed Date:  2006-06-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  15740290R     Medline TA:  Br Poult Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  50-6     Citation Subset:  IM    
Department of Animal Production, University of Murcia, Murcia, Spain.
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MeSH Terms
Animal Feed
Anti-Bacterial Agents / pharmacology
Blood / drug effects*,  metabolism
Chickens / anatomy & histology,  blood,  metabolism,  physiology*
Dietary Supplements*
Digestion / drug effects*
Dose-Response Relationship, Drug
Feeding Behavior
Formic Acids / pharmacology*
Hydrogen-Ion Concentration
Intestines / anatomy & histology*,  drug effects*,  metabolism
Oligosaccharides / pharmacology
Weight Gain / drug effects
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Formic Acids; 0/Oligosaccharides; 11051-71-1/avilamycin; 64-18-6/formic acid

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