Document Detail


Effect of folic acid treatment in the fragile X syndrome.
MedLine Citation:
PMID:  4006270     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of folic acid intake on the frequency of fragile X positive cells and some behavioural characteristics were evaluated in 5 boys and 4 adult males with the fragile X syndrome. The expression of fragile X was nullified in 6 and decreased in 3 of the 9 patients. Behavioural and motor ability were considered to have improved in 4 of the 5 boys but not in the 4 adults with fragile X syndrome.
Authors:
K H Gustavson; K Dahlbom; A Flood; G Holmgren; H K Blomquist; G Sanner
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical genetics     Volume:  27     ISSN:  0009-9163     ISO Abbreviation:  Clin. Genet.     Publication Date:  1985 May 
Date Detail:
Created Date:  1985-08-22     Completed Date:  1985-08-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0253664     Medline TA:  Clin Genet     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  463-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Behavior / drug effects
Child
Child, Preschool
Chromosome Fragility
Folic Acid / therapeutic use*
Fragile X Syndrome / drug therapy*,  psychology
Humans
Male
Middle Aged
Sex Chromosome Aberrations / drug therapy*
Time Factors
Chemical
Reg. No./Substance:
59-30-3/Folic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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