Document Detail


Effect of flow on the resistance of modelled femoral artery stenoses.
MedLine Citation:
PMID:  8813786     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An accurate model of the pressure-flow relationship of a stenosis is necessary for the correct interpretation of haemodynamic measurements. Modelled femoral artery stenoses were tested in vitro and the pressure drop: flow ratio (resistance) was most accurately represented by a fixed component (Rf) combined with a variable component (Rv) that increased linearly with flow (Q) such that Rv = SvQ. For stenoses of 68-94 per cent area, Rf increased from 3.2 to 77.7 milliperipheral resistance units (mPRU), while Sv increased from 0.009 to 0.578 mPRU ml-1 min and Rv was dominant for physiological flow rates. It was concluded that the approximation of a significant stenosis to a fixed resistance is incorrect.
Authors:
S R Dodds; N K Bourne; A D Chant
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of surgery     Volume:  83     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  1996 Jul 
Date Detail:
Created Date:  1996-10-22     Completed Date:  1996-10-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  957-61     Citation Subset:  AIM; IM    
Affiliation:
Department of Vascular Surgery, Royal South Hants Hospital, Southampton, UK.
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MeSH Terms
Descriptor/Qualifier:
Blood Flow Velocity
Blood Pressure / physiology
Constriction, Pathologic / physiopathology
Femoral Artery / physiopathology*
Humans
Models, Biological
Peripheral Vascular Diseases / pathology,  physiopathology
Vascular Resistance / physiology*
Comments/Corrections
Comment In:
Br J Surg. 1997 Feb;84(2):279-81   [PMID:  9052458 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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