Document Detail

Effect of the final coronary arterial diameter after coronary angioplasty on heart rate variability responses.
MedLine Citation:
PMID:  12049681     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Autonomic nervous system dysfunction and reduced heart rate variability (HRV) after percutaneous transluminal coronary angioplasty (PTCA) were reported in patients with coronary artery disease. However, factors related to reduced HRV are not clearly demonstrated. The aim of the present study was to assess the relationship between HRV indices and the final coronary arterial luminal diameter after PTCA. METHODS: Twenty-seven patients (23 male, 4 female, mean age: 52.5 +/- 7.1 years) with single vessel disease were included in the study. PTCA was performed in all patients. Low-frequency power (LFP), high-frequency power (HFP), and total power (TP) were calculated by using frequency-domain analysis of HRV. All examinations were performed 24 hours before, and 24 hours, 10 days, and 30 days after PTCA. The patients were divided into groups according to the PTCA restenosis risk score, the degree of dilatation, and revascularization after coronary angioplasty. RESULTS: The groups were comparable for age, gender, and coronary artery risk factors. HRV was found to be reduced in 76% of patients. Reduction in HRV after PTCA was significantly related to the PTCA risk score and the degree of revascularization (r = 0.48, P < 0.01 and r = 0.50, P < 0.008). Reduction in HRV was more significant in patients with previous myocardial infarction (P < 0.05). Recovery of HRV occurred on the tenth day after PTCA. CONCLUSION: Transient and rapidly recovered, especially parasympathetically modulated HRV reduction occurred after PTCA in patients with single-vessel disease. HRV reduction is associated with PTCA restenosis risk score and the degree of revascularization as invasive feature of angioplasty, hence it may be related to reperfusion.
Mehmet Kanadasi; Gulmira Kudaiberdieva; Ahmet Birand
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc     Volume:  7     ISSN:  1082-720X     ISO Abbreviation:  Ann Noninvasive Electrocardiol     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-06-06     Completed Date:  2002-07-30     Revised Date:  2008-03-10    
Medline Journal Info:
Nlm Unique ID:  9607443     Medline TA:  Ann Noninvasive Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  106-13     Citation Subset:  IM    
Department of Cardiology, School of Medicine, Cukurova University, 01330 Yüreğir, Adana, Turkey.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary*
Autonomic Nervous System / physiopathology*
Coronary Disease / physiopathology*,  therapy
Coronary Vessels / pathology*
Heart Rate / physiology*
Middle Aged
Comment In:
Ann Noninvasive Electrocardiol. 2002 Apr;7(2):83-5   [PMID:  12049677 ]

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