Document Detail

Effect of filtration on complications of postoperative intravenous therapy.
MedLine Citation:
PMID:  507079     Owner:  NLM     Status:  MEDLINE    
The incidence of intravenous complications (phlebitis) and the length of hospital stay in postoperative patients whose infusions were filtered through inline final filters were compared with those in patients whose infusions were not filtered. Identical i.v. solutions were administered to 150 postoperative orthopedic patients randomly assigned to three study groups: control (no filter), 5-micrometers membrane filter and 0.45-micrometers membrane filter. An i.v. therapy team of seven nurses inspected patients for phlebitis. The phlebitis rate of the control group (27%) was significantly greater (p less than 0.05) than that of the 0.45-micrometers filter group (6%) but not significantly different (p less than 0.9) from that of the 5-micrometers filter group (22%). In a subgroup of 104 patients undergoing total hip replacement, the mean reduction in length of postoperative hospital stay compared with the control group (13.6 days) was: 5-micrometers filter group--3.4 days (p less than 0.01); and 0.45-micrometer filter group--3.3 days (p less than 0.01). The results suggest that final filters can be used to reduce the incidence of phlebitis-related i.v. complications and thereby reduce the length of hospital stay.
W J Rusho; J N Bair
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  American journal of hospital pharmacy     Volume:  36     ISSN:  0002-9289     ISO Abbreviation:  Am J Hosp Pharm     Publication Date:  1979 Oct 
Date Detail:
Created Date:  1980-01-24     Completed Date:  1980-01-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370474     Medline TA:  Am J Hosp Pharm     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1355-6     Citation Subset:  IM    
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MeSH Terms
Cephalothin / administration & dosage
Evaluation Studies as Topic
Infusions, Parenteral / adverse effects,  instrumentation*
Length of Stay
Micropore Filters*
Phlebitis / epidemiology*
Postoperative Care
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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