Document Detail

Effect of fiberoptic bronchoscopy on arterial blood gases and cardiac rhythm at a moderate altitude of 2250 meters.
MedLine Citation:
PMID:  10862312     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To study the effects of fiberoptic bronchoscopy (FOB) at an altitude of 2250 m on arterial blood gases (ABG) and cardiac rhythm abnormality. METHODS: Fifty consecutive patients undergoing fiberoptic bronchoscopy were evaluated for the arterial blood gases and cardiac rhythm changes at Shimla (a moderate altitude of 2250 m), where there is a state of ambient hypoxia. RESULTS: The changes were noted in five stages ranging from the levels before the procedure till 15 minutes after the completion of the procedure. The mean fall in PaO2 levels in this study was 8 +/- 2.45 mm Hg and the fall was maximum at the end of procedure. Both smokers and nonsmokers showed a significant fall but the fall was more severe in smokers. The mean fall in SaO2 in this study was 3%. The increase in heart rate and blood pressure during FOB was significant as compared to baseline levels. There was no significant change in PH, PaCO2, HCO3. The commonest rhythm abnormality noted was sinus tachycardia which was well tolerated. No major cardiac arrhythmia was noted. It was further seen that the duration of the procedure and type of special procedure undertaken did not effect the levels significantly. Cyanosis was the commonest complication encountered (36%) and was seen more frequently in smokers and those with age more than 40 years. It was observed during the induction of bronchoscope and also during the further negotiation of the bronchoscope into the smaller branches of bronchial tree. CONCLUSION: The changes in ABG and cardiac rhythm are comparable to the studies at sea level except the increased incidence of cyanosis.
G D Sharma; S K Bansal; S Kashyap; D Kapoor
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the Association of Physicians of India     Volume:  47     ISSN:  0004-5772     ISO Abbreviation:  J Assoc Physicians India     Publication Date:  1999 Nov 
Date Detail:
Created Date:  2000-07-17     Completed Date:  2000-07-17     Revised Date:  2004-11-22    
Medline Journal Info:
Nlm Unique ID:  7505585     Medline TA:  J Assoc Physicians India     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  1056-9     Citation Subset:  IM; S    
Dept. of Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh.
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MeSH Terms
Altitude Sickness / physiopathology*
Anoxia / physiopathology
Carbon Dioxide / blood*
Heart Rate / physiology*
Middle Aged
Oxygen / blood*
Risk Factors
Tachycardia, Sinus / physiopathology
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen
Comment In:
J Assoc Physicians India. 2002 Feb;50:286-7   [PMID:  12038672 ]

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