Document Detail


Effect of fertilization by intracytoplasmic sperm injection versus conventional insemination on embryo cleavage rates.
MedLine Citation:
PMID:  21077519     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To determine if fertilization by conventional oocyte insemination vs intracytoplasmic sperm injection (ICSI) causes any difference in the maximum number of blastomeres of fresh or frozen thawed embryos transferred.
METHODS: Retrospective evaluation of all in vitro fertilization (IVF) cycles over a 10-year period in cycles having a 2 embryos transferred where the semen analysis was normal except for strict morphology which was allowed to be 2-5% normal. The percentage of the maximum number of blastomeres in any transfers was compared according to the method of insemination.
RESULTS: There were no differences in the maximum blastomere numbers in cycles where there was conventional insemination vs ICSI.
CONCLUSIONS: Though higher pregnancy rates have been found following the transfer of embryos derived from conventional oocyte insemination vs ICSI, and higher pregnancy rates were found following single embryo day 3 transfers with embryos with more blastomeres, the beneficial effect of conventional insemination does not seem to be related to forming embryos with more rapid cleavage.
Authors:
J H Check; A Bollendorf; E Dix; D Katsoff
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical and experimental obstetrics & gynecology     Volume:  37     ISSN:  0390-6663     ISO Abbreviation:  Clin Exp Obstet Gynecol     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-16     Completed Date:  2010-12-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802110     Medline TA:  Clin Exp Obstet Gynecol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  183-4     Citation Subset:  IM    
Affiliation:
The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA. laurie@ccivf.com
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MeSH Terms
Descriptor/Qualifier:
Blastomeres*
Cleavage Stage, Ovum*
Embryo Implantation
Embryo Transfer
Female
Fertilization in Vitro*
Humans
Pregnancy
Pregnancy Rate
Retrospective Studies
Sperm Injections, Intracytoplasmic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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