Document Detail

Effect of fenugreek fiber on satiety, blood glucose and insulin response and energy intake in obese subjects.
MedLine Citation:
PMID:  19353539     Owner:  NLM     Status:  MEDLINE    
Eighteen healthy obese subjects participated in a single blind, randomized, crossover study of three test breakfasts, containing 0 g (control), 4 g or 8 g of isolated fenugreek fiber. Subjects recorded ratings of hunger, satiety, fullness and prospective food consumption using visual analog scales (VAS) every 30 min for 3.5 h. Postprandial blood glucose and insulin responses were measured. Energy intake from an ad libitum lunch buffet and for the remainder of the day was assessed. The 8 g dose of fenugreek fiber significantly increased mean ratings of satiety and fullness, and reduced ratings of hunger and prospective food consumption (P < 0.05). Palatability was significantly reduced with increasing doses of fenugreek fiber (P < 0.05). No differences were observed for area under the curve (AUC) for blood glucose among treatments. An increase in insulin AUC was found with 8 g fenugreek fiber. Energy intake at an ad libitum lunch buffet was significantly lower for 8 g than 4 g fenugreek fiber, but not significantly different from control, although there was a trend towards a lower intake (p = 0.11). No differences were observed for energy intake for the remainder of the day. Fenugreek fiber (8 g) significantly increased satiety and reduced energy intake at lunch, suggesting it may have short-term beneficial effects in obese subjects. Satiety results were not related to postprandial blood glucose.
Jocelyn R Mathern; Susan K Raatz; William Thomas; Joanne L Slavin
Related Documents :
22069729 - Shiga toxin interaction with human intestinal epithelium.
15026979 - Optimal body size and energy expenditure during winter: why are voles smaller in declin...
16269339 - Divergence of melanocortin pathways in the control of food intake and energy expenditure.
9186769 - Food intake regulation in children. fat and sugar substitutes and intake.
17604749 - Children's preference for large portions: prevalence, determinants, and consequences.
19776139 - Are energy-dense foods really cheaper? reexamining the relation between food price and ...
4095189 - Effects of pre-feeding on food-approach latency and food consumption speed in food depr...
9929399 - Growth of amoebae and flagellates on bacteria deposited on filters.
18803729 - Production and shelf stability of multiple-fortified quick-cooking rice as a complement...
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Phytotherapy research : PTR     Volume:  23     ISSN:  1099-1573     ISO Abbreviation:  Phytother Res     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-29     Completed Date:  2010-02-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8904486     Medline TA:  Phytother Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  1543-8     Citation Subset:  IM    
Department of Food Science and Nutrition, University of Minnesota, St Paul, MN 55108, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Area Under Curve
Blood Glucose / drug effects*
Cross-Over Studies
Eating / drug effects,  physiology
Energy Intake / drug effects*,  physiology
Hunger / physiology
Insulin / blood*
Middle Aged
Plant Extracts / pharmacology*
Satiation / physiology
Single-Blind Method
Young Adult
Grant Support
Reg. No./Substance:
0/Blood Glucose; 0/Plant Extracts; 11061-68-0/Insulin; 68990-15-8/fenugreek seed meal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Structure-activity relationship studies on the mosquito toxicity and biting deterrency of callicarpe...
Next Document:  Phytotoxic aromatic constituents of Oxalis pes-caprae.