| Effect of feeding regulation measures for establishing esophageal channel function in neoesophagus created with a nitinol artificial esophagus. | |
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MedLine Citation:
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PMID: 22865478 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Purpose: This study attempted to observe the effect of feeding regulation measures (FRM) for the construction of an esophageal channel function in a neoesophagus using an artificial nitinol esophagus. Methods: Experiments were divided among groups: group 1, receiving FRM; and group 2, the non-feeding regulation measures (NFRM) group. Results: Ten pigs survived for 6 months without any complications such as anastomotic leakage. The shedding time of the artificial esophagus in group 1 was significantly delayed in comparison with group 2 (>180 ± 0.0 days vs. 75.6 ± 27.1 days, respectively, p<0.05). In group 1, the weight changes at 3 and 6 months postoperation were significantly different in comparison with preoperative values (t = 14.86, 9.17 > 2.78, respectively; p<0.05). In group 2, the weight changes at 3 and 6 months postoperation were significantly different in comparison with preoperative values (t = 7.95, 11.37 > 2.78, respectively; p<0.05). Conclusions: FRM not only effectively delayed the shedding time of the artificial esophagus but also played a role in protecting the neoesophagus from stenosis, by functioned as a bougienage after artificial esophagus sloughing. Therefore, FRM is an effective way for establishing a stable eating channel in the neoesophagus when using a nitinol composite artificial esophagus to replace the resected segment of an intrathoracic esophagus. |
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Authors:
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Jian-Hui Liang; Pin Cai; Zhon-Ran Luo; Xian-Liang Liang; Xing Zhou |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-7-19 |
Journal Detail:
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Title: The International journal of artificial organs Volume: - ISSN: 1724-6040 ISO Abbreviation: Int J Artif Organs Publication Date: 2012 Jul |
Date Detail:
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Created Date: 2012-8-6 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7802649 Medline TA: Int J Artif Organs Country: - |
Other Details:
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Languages: ENG Pagination: 0 Citation Subset: - |
Affiliation:
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Department of Chest Surgery, The Second Affiliated Hospital of Guangzhou Medical College, Institute of Guangzhou Cardiovascular Diseases, Guangzhou - PR China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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