| Effect of feeding Mucuna pruriens on helminth parasite infestation in lambs. | |
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MedLine Citation:
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PMID: 19969060 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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ETHNOPHARMACOLOGICAL RELEVANCE: Mucuna pruriens is a tropical legume anecdotally reputed to have anthelmintic properties. This study was conducted to examine the validity of such claims. AIM OF THE STUDY: The aim of this study was to determine if ingestion of Mucuna seeds reduces helminth parasite infestation in lambs. MATERIALS AND METHODS: Thirty-six Dorper x Katahdin ram lambs were assigned to three treatments, a cottonseed meal based control diet, a diet in which Mucuna replaced cottonseed meal and the control diet with levamisole (7.5mg/kg body weight) administration. All diets were isonitrogenous and isocaloric. The 12 lambs in each treatment were assigned randomly to 4 pens, each containing 3 lambs. Lambs were trickle infected three times per week by gavage with infectious Haemonchus contortus larvae (2000 larvae/lamb) for 3 weeks. RESULTS: Levamisole treatment decreased fecal egg counts by 87% and abomasal worm counts by 83%. Mucuna intake did not statistically affect fecal egg counts or abomasal worm counts, though numerical (P>0.10) reductions of 7.4% and 18.1%, respectively were evident. Anemia indicators, feed intake, and lamb growth were unaffected by treatment. CONCLUSIONS: Levamisole reduced the Haemonchus parasite burden in lambs significantly but feeding Mucuna reduced the burden by levels unlikely to eliminate the clinical effects of parasitism. |
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Authors:
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C M Huisden; A T Adesogan; J M Gaskin; C H Courtney; A M Raji; T Kang |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial Date: 2009-12-05 |
Journal Detail:
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Title: Journal of ethnopharmacology Volume: 127 ISSN: 1872-7573 ISO Abbreviation: J Ethnopharmacol Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-15 Completed Date: 2010-08-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7903310 Medline TA: J Ethnopharmacol Country: Ireland |
Other Details:
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Languages: eng Pagination: 669-73 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Department of Animal Sciences, Institute of Food and Agricultural Science, University of Florida, Gainesville, FL 32611, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antinematodal Agents / pharmacology, therapeutic use* Cottonseed Oil Diet Haemonchiasis / drug therapy, parasitology, veterinary* Haemonchus / drug effects Levamisole / pharmacology, therapeutic use* Mucuna* Parasite Egg Count Phytotherapy* Plant Preparations / pharmacology, therapeutic use* Seeds Sheep Sheep Diseases / drug therapy*, parasitology |
| Chemical | |
Reg. No./Substance:
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0/Antinematodal Agents; 0/Cottonseed Oil; 0/Plant Preparations; 14769-73-4/Levamisole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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