Document Detail

Effect of exercise training on multiple respiratory variables in patients with coronary artery disease: correlation with change in exercise capacity.
MedLine Citation:
PMID:  1763828     Owner:  NLM     Status:  MEDLINE    
Multiple measurements of pulmonary function were performed during exercise testing in 29 patients with coronary artery disease (CAD) before and after exercise training. Following training, significant increases in oxygen consumption (VO2), carbon dioxide production (VCO2), and peak flow at maximal exercise were seen as compared with pretraining values (p less than .01), but not in any other respiratory variables. Only the peak respiratory exchange ratio (RER) achieved during pretraining exercise testing and peak values of minute ventilation (VT), respiratory rate, and VCO2 during a posttraining exercise test showed significant correlations with the change in maximum VO2 following exercise training (p less than .05). Significant correlations were also found among VT, VCO2, and peak flow at peak exercise following exercise training and the change in exercise duration between pretraining and posttraining stress tests. Of 22 patients evaluated with thallium 201 scintigraphy during their pretraining exercise test, 11 developed ischemic ST depression or a reversible perfusion defect. No significant differences in pulmonary function measurements during exercise testing were seen between patients who developed ischemia and those who did not. However, the change in peak metabolic equivalents (METS) achieved between pretraining and posttraining exercise was significantly greater in patients who developed ischemia (.836 +/- 1.003 versus .091 +/- .481, p less than .05). These results indicate that exercise training in patients with CAD is not associated with significant changes in most measurements of pulmonary function and, with the exception of RER at peak exercise, pretraining measurements do no show a significant correlation with changes in exercise capacity.
H Stratmann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Angiology     Volume:  42     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1992-02-11     Completed Date:  1992-02-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  948-56     Citation Subset:  IM; S    
Department of Cardiology, St. Louis Veterans Administration Medical Center, St. Louis, Missouri.
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MeSH Terms
Blood Pressure / physiology
Carbon Dioxide / metabolism
Coronary Disease / physiopathology*,  radionuclide imaging,  rehabilitation
Exercise / physiology*
Exercise Test
Exercise Therapy*
Heart / radionuclide imaging
Heart Rate / physiology
Middle Aged
Oxygen / blood
Oxygen Consumption / physiology
Pulmonary Gas Exchange / physiology
Respiration / physiology*
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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