Document Detail


Effect of exercise training and diet modification on serum lipids and lipoproteins in coronary artery disease patients treated with thiazides.
MedLine Citation:
PMID:  4075609     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effects of chronic exercise training and diet modification on serum lipids and lipoproteins were measured in 17 hypertensive males and 41 normotensive males with documented coronary artery disease (CAD). Exercise consisted of aerobic activities which were performed at approximately 75-85% of the symptom-limited maximum heart rate for 30-40 minutes, three times weekly for 3 months. Each participant's diet was also controlled, the recommended daily intake of fat and cholesterol was no more than 40 g/day and 200 mg/day, respectively. Significant increases in estimated VO2max and total cholesterol/high density lipoprotein (HDL) and a significant decrease in serum triglycerides were documented after training. Significant differences in serum cholesterol and triglycerides between the nondiuretic and diuretic patients were also noted. No significant changes were found in low density lipoprotein (LDL), HDL, or body weight. Vigorous aerobic training and diet modification can favorably modify the deleterious effects of diuretic medications on serum triglycerides and total cholesterol/HDL in patients with documented CAD.
Authors:
S J Kahrs; C Weinstein; J Douwes; J Alexander; S Weinstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical cardiology     Volume:  8     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1985 Dec 
Date Detail:
Created Date:  1986-01-31     Completed Date:  1986-01-31     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  636-40     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Benzothiadiazines*
Combined Modality Therapy
Coronary Disease / blood,  therapy*
Diet, Reducing
Dietary Fats* / administration & dosage*
Diuretics
Humans
Hypertension / blood,  therapy*
Lipids / blood*
Lipoproteins / blood*
Male
Middle Aged
Physical Exertion*
Sodium Chloride Symporter Inhibitors / therapeutic use*
Chemical
Reg. No./Substance:
0/Benzothiadiazines; 0/Dietary Fats; 0/Diuretics; 0/Lipids; 0/Lipoproteins; 0/Sodium Chloride Symporter Inhibitors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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