Document Detail

Effect of exercise training on central aortic pressure wave reflection in coronary artery disease.
MedLine Citation:
PMID:  15177529     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Arterial stiffness is an important factor for cardiovascular performance and a predictor of cardiovascular risk. We investigated the effect of exercise training on arterial stiffness in coronary artery disease (CAD). METHODS: Arterial stiffness was assessed before and after 12 weeks of either exercise training or standard care in CAD patients. Arterial stiffness was evaluated by aortic augmentation index and time delay of the reflected wave (Deltat) using the SphygmoCor system. RESULTS: The augmentation index decreased (30% v 26%, P <.05) and Deltat increased (136 msec v 144 msec, P <.05) in patients with CAD after 12 weeks of exercise. CONCLUSION: These results suggest that endurance exercise training improves systemic arterial stiffness in individuals with CAD.
David G Edwards; Richard S Schofield; Peter M Magyari; Wilmer W Nichols; Randy W Braith
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of hypertension     Volume:  17     ISSN:  0895-7061     ISO Abbreviation:  Am. J. Hypertens.     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-06-04     Completed Date:  2004-11-06     Revised Date:  2009-02-24    
Medline Journal Info:
Nlm Unique ID:  8803676     Medline TA:  Am J Hypertens     Country:  United States    
Other Details:
Languages:  eng     Pagination:  540-3     Citation Subset:  IM    
Department of Kinesiology, University of New Hampshire, Durham, NH 03824, USA.
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MeSH Terms
Aorta / physiopathology*
Blood Pressure / physiology*
Coronary Artery Disease / physiopathology*,  therapy*
Diastole / physiology
Exercise Therapy*
Heart Rate / physiology
Middle Aged
Systole / physiology
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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