| Effect of exercise therapy on monocyte and neutrophil counts in overweight women. | |
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MedLine Citation:
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PMID: 20145432 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: It has been well known that physical inactivity is associated with a significantly higher incidence of coronary artery disease. This study aimed to test our hypothesis that endurance aerobic exercise training has cardiovascular protective effects as a result of inhibiting inflammatory processes. METHODS: Forty-two overweight women [age, 53.4 +/- 9.8 years; body mass index (BMI), 28.0 +/- 2.8] received electric bicycle ergometer exercise therapy at the lactate threshold intensity for 30 to 60 minutes per day, 1 to 6 times per week for 6 weeks. The exercise training was performed within the possible load (exercise duration and frequency) for each subject. RESULTS: Leukocyte, monocyte, and neutrophil counts significantly decreased after the exercise therapy (P < 0.05). In simple regression analysis, percent changes in monocyte and neutrophil counts were correlated with percent changes in fasting triglyceride levels, insulin sensitivity index, BMI, and maximal oxygen uptake (VO2max). In stepwise multiple regression analysis, the percent change in monocyte counts was associated with percent changes in fasting triglyceride and VO2max (r = 0.368, P < 0.001), and the percent change in neutrophil counts was associated with percent changes in insulin sensitivity index and BMI (r = 0.292, P < 0.001). CONCLUSIONS: Endurance aerobic exercise training can influence some inflammatory processes. Furthermore, increased aerobic capacity may be antiinflammatory and have cardiovascular protective effects in overweight women. |
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Authors:
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Ryoma Michishita; Naoko Shono; Teruo Inoue; Toshiyuki Tsuruta; Koichi Node |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of the medical sciences Volume: 339 ISSN: 1538-2990 ISO Abbreviation: Am. J. Med. Sci. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-10 Completed Date: 2010-03-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370506 Medline TA: Am J Med Sci Country: United States |
Other Details:
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Languages: eng Pagination: 152-6 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiovascular and Renal Medicine, Saga University Faculty of Medicine, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Cell Count Exercise Therapy* Female Humans Leukocyte Count Middle Aged Monocytes / physiology* Neutrophils / physiology* Overweight / therapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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