| Effect of exercise mode on blood glucose disposal during physiological hyperinsulinaemia in humans. | |
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MedLine Citation:
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PMID: 12665988 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to compare whole-body glucose uptake in cycling and running performed during physiological hyperinsulinaemia. On three occasions, seven male subjects underwent a hyperinsulinaemic (30 mU m(-2) min(-1)), euglycaemic (5 mmol l(-1)) clamp for 120 min. On one occasion, subjects rested for the duration of the trial (CON). On the other two occasions, after an initial resting period of 30 min, subjects either cycled (CYC) or ran (RUN) for 90 min at 65% of maximal O(2) uptake (VO(2max)). Insulin infusion resulted in physiological hyperinsulinaemia that was maintained for the duration of each trial [CON: 61 (3) mU l(-1); CYC: 77 (7) mU l(-1); RUN: 77 (5) mU l(-1)]. The rate of glucose uptake was greater during RUN than during CYC [last 30 min of exercise: 140 (4) vs 109 (8) micromol kg(-1) min(-1), respectively; P <0.01]. A differential amount of active muscle mass and/or muscle fibre type recruitment might account for the observed differences in glucose disposal between cycling and running. |
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Authors:
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K Tsintzas; E J Simpson; N Seevaratnam; S Jones |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial Date: 2003-02-01 |
Journal Detail:
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Title: European journal of applied physiology Volume: 89 ISSN: 1439-6319 ISO Abbreviation: Eur. J. Appl. Physiol. Publication Date: 2003 Apr |
Date Detail:
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Created Date: 2003-03-31 Completed Date: 2003-07-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 100954790 Medline TA: Eur J Appl Physiol Country: Germany |
Other Details:
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Languages: eng Pagination: 217-20 Citation Subset: IM |
Affiliation:
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School of Biomedical Sciences, Nottingham University Medical School, Queen's Medical Centre, Nottingham, NG7 2UH, UK. kostas.tsintzas@nottingham.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bicycling / physiology* Blood Glucose / analysis* Fasting / blood Glucose / metabolism Humans Hyperinsulinism / blood* Infusions, Intravenous Insulin / administration & dosage Male Running / physiology* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 11061-68-0/Insulin; 50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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