Document Detail


Effect of exercise on met-enkephalin in unfit and superfit individuals.
MedLine Citation:
PMID:  2598973     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twenty-four unfit volunteers and twenty-three superfit athletes were subjected to a progressive intensity treadmill exercise to total exhaustion in order to study the plasma met-enkephalin response to exercise. Blood samples were collected before and 5 min post-exercise. The basal met-enkephalin levels were significantly higher in the superfit individuals (180 fmol.ml-1) than in the unfit individuals (126 fmol.ml-1). Post-exercise the increase from basal levels of plasma met-enkephalin was significantly higher in the superfit athletes (180-278 fmol.ml-1) than in the unfit individuals (126-157 fmol.ml-1). The magnitude of the met-enkephalin responses to exercise therefore appears to be dependent on the amount of work performed and the degree of previous physical training. Peripherally circulating opioid peptides may, therefore, possibly play a role in the body's adaptation to exercise training.
Authors:
K De Sommers; S F Simpson; J M Loots; E C Meyer; A Dettweiler; H O Daehne
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of clinical pharmacology     Volume:  37     ISSN:  0031-6970     ISO Abbreviation:  Eur. J. Clin. Pharmacol.     Publication Date:  1989  
Date Detail:
Created Date:  1990-02-02     Completed Date:  1990-02-02     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  1256165     Medline TA:  Eur J Clin Pharmacol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  399-400     Citation Subset:  IM    
Affiliation:
Department of Pharmacology, University of Pretoria, South Africa.
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MeSH Terms
Descriptor/Qualifier:
Adult
Enkephalin, Methionine / blood*
Humans
Physical Exertion / physiology*
Physical Fitness / physiology*
Chemical
Reg. No./Substance:
58569-55-4/Enkephalin, Methionine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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