| Effect of exercise on met-enkephalin in unfit and superfit individuals. | |
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MedLine Citation:
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PMID: 2598973 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-four unfit volunteers and twenty-three superfit athletes were subjected to a progressive intensity treadmill exercise to total exhaustion in order to study the plasma met-enkephalin response to exercise. Blood samples were collected before and 5 min post-exercise. The basal met-enkephalin levels were significantly higher in the superfit individuals (180 fmol.ml-1) than in the unfit individuals (126 fmol.ml-1). Post-exercise the increase from basal levels of plasma met-enkephalin was significantly higher in the superfit athletes (180-278 fmol.ml-1) than in the unfit individuals (126-157 fmol.ml-1). The magnitude of the met-enkephalin responses to exercise therefore appears to be dependent on the amount of work performed and the degree of previous physical training. Peripherally circulating opioid peptides may, therefore, possibly play a role in the body's adaptation to exercise training. |
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Authors:
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K De Sommers; S F Simpson; J M Loots; E C Meyer; A Dettweiler; H O Daehne |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of clinical pharmacology Volume: 37 ISSN: 0031-6970 ISO Abbreviation: Eur. J. Clin. Pharmacol. Publication Date: 1989 |
Date Detail:
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Created Date: 1990-02-02 Completed Date: 1990-02-02 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 1256165 Medline TA: Eur J Clin Pharmacol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 399-400 Citation Subset: IM |
Affiliation:
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Department of Pharmacology, University of Pretoria, South Africa. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Enkephalin, Methionine / blood* Humans Physical Exertion / physiology* Physical Fitness / physiology* |
| Chemical | |
Reg. No./Substance:
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58569-55-4/Enkephalin, Methionine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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