| Effect of exercise on acid-base status and ventilatory kinetics. | |
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MedLine Citation:
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PMID: 9741659 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The normal respiratory responses and changes in acid base status in twenty normal height, weight and age matched subjects were studied; using Auto Spiro AS 300 spirometer for ventilatory parameters and NOVA stat profile 3 analyser for gas analysis. Each subject performed a progressive incremental treadmill exercise by Bruce protocol to their symptom limited maximum. Minute ventilation (VE), tidal volume (VT) and frequency of respiration (f) increased significantly (P<0.001). Acidosis occured following exercise as pH of arterialized venous blood declined significantly (P<0.05). Gas analysis of arterialized venous blood showed a rise in pO2 (P<0.001) and a fall in pCO2 (P<0.001). Recovery of acid base status as well as gaseous pressure in blood did not occur after 10 min. Expired gas pCO2 declined significantly (P<0.05) and pO2 increase significantly (P<0.05). These pressures returned to resting levels 10 min after exercise. Thus in normal young adults heavy exercise caused an increment in ventilatory kinetics producing hyperpnoea which recovers after a rest of 10 min. Acidosis stimulates the respiratory centre to cause hyperventilation which tries to meet the added metabolic demands of strenuous exercise. |
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Authors:
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M S Phatak; G A Kurhade; S B Kaore; G C Pradhan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian journal of physiology and pharmacology Volume: 42 ISSN: 0019-5499 ISO Abbreviation: Indian J. Physiol. Pharmacol. Publication Date: 1998 Jul |
Date Detail:
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Created Date: 1998-12-07 Completed Date: 1998-12-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0374707 Medline TA: Indian J Physiol Pharmacol Country: INDIA |
Other Details:
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Languages: eng Pagination: 417-20 Citation Subset: IM |
Affiliation:
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Department of Physiology, Govt. Medical College, Nagpur. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acidosis Adult Carbon Dioxide Exercise / physiology* Humans Lung / physiology* Male Oxygen Pulmonary Ventilation* Respiratory Function Tests Tidal Volume |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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