Document Detail

Effect of ethanol and commonly ingested alcoholic beverages on gastric emptying and gastrointestinal transit.
MedLine Citation:
PMID:  1392416     Owner:  NLM     Status:  MEDLINE    
Acute ingestion of pure ethanol has been reported to delay gastric emptying and to enhance the propulsive movements of the intestine. The aim of the present study was to investigate the comparative effect of beer (7.0% v/v), white wine (7.5% v/v), ethanol (7.5% v/v), and water on the gastric emptying of a liquid test meal and on the gastrocaecal transit time of lactulose added to the test meal. Gastric liquid emptying was assessed by means of a nasogastric intubation technique using polyethylene glycol 4000 as the non-absorbable marker. The gastrocaecal transit time was evaluated by a hydrogen breath test. Beer (P less than 0.001) and white wine (P less than 0.05) significantly accelerated gastric emptying in comparison with ethanol of the same concentration. The gastrocaecal transit time was significantly shorter when the liquid meal was administered with beer compared with ethanol (P less than 0.005) and water (P less than 0.01). The constituents in beer and white wine responsible for our observations remain to be found.
A Pfeiffer; B Högl; H Kaess
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Clinical investigator     Volume:  70     ISSN:  0941-0198     ISO Abbreviation:  Clin Investig     Publication Date:  1992 Jun 
Date Detail:
Created Date:  1992-11-02     Completed Date:  1992-11-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9207154     Medline TA:  Clin Investig     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  487-91     Citation Subset:  IM    
II. Medizinische Abteilung, Städtisches Krankenhaus München-Bogenhausen.
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MeSH Terms
Alcoholic Beverages*
Breath Tests
Ethanol / pharmacology*
Gastric Emptying / drug effects*
Gastrointestinal Transit / drug effects*
Lactulose / pharmacokinetics
Polyethylene Glycols / diagnostic use
Reg. No./Substance:
0/Polyethylene Glycols; 4618-18-2/Lactulose; 64-17-5/Ethanol; 7732-18-5/Water

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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