Document Detail

Effect of environmental supplementation of iodine on infant mortality and growth in children in Xinjiang, China
MedLine Citation:
PMID:  12411089     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To study the effect of iodine supplementation on infant mortality and growth in Xinjiang. METHODS: Urine iodine, height and head circumference (HC) of children aged 5 years in two townships was measured before and yearly after iodine supplementation of irrigation water. Height and HC were expressed as Z scores (United States children used as the reference group). Neonatal and infant mortality rates were obtained from official records in three counties from 1988 to 1999, and analyzed by a logistic regression model. RESULTS: The odds ratio of infant mortality decreased 56.49% and neonatal mortality 65.71% respectively after iodination; there was no significant difference in the odds ratio of infant or neonatal mortality between experimental and control areas without iodination. In Langru township, the mean height of 5 year-old children increased from 95 cm in 1992 to 106.9 cm in 1998 - 1999, and HC from 48.4 cm to 50.5 cm. Median urine iodine increased from <10 to 176 micro g/L. In Bakechi township, mean height increased from 91 cm in 1993 to 106.5 cm in 1998 - 1999, HC from 48.7 to 49.6 cm, and median urine iodine from 39 to 138 micro g/L. CONCLUSION: In Xinjiang, adequate iodine treatment markedly decreased infant and neonatal mortality, and largely preventing stunting of height and HC in children.
Qiang Ren; DeLong Gr; Xueyi Cao; Shaohua Wang; Xinmin Jiang; Jiyong Jiang; Erdang Ma; Karen O'Donnell
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Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi     Volume:  23     ISSN:  0254-6450     ISO Abbreviation:  Zhonghua Liu Xing Bing Xue Za Zhi     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-11-04     Completed Date:  2002-12-04     Revised Date:  2009-12-23    
Medline Journal Info:
Nlm Unique ID:  8208604     Medline TA:  Zhonghua Liu Xing Bing Xue Za Zhi     Country:  China    
Other Details:
Languages:  chi     Pagination:  198-202     Citation Subset:  IM    
Institute of Population Research, Xinjiang University, Urumqi 830046, China.
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MeSH Terms
Body Height / drug effects*
Child Development / drug effects*
Child, Preschool
Infant Mortality* / trends
Iodine / analysis,  pharmacology*,  urine
Logistic Models
Odds Ratio
Plants / chemistry
Soil / analysis
Thyroid Gland / chemistry
Time Factors
Water / chemistry
Reg. No./Substance:
0/Soil; 7553-56-2/Iodine; 7732-18-5/Water

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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