| Effect of environmental hyperthermia on gastrin, somatostatin and motilin in rat ulcerated antral mucosa. | |
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MedLine Citation:
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PMID: 15526379 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To study the effect of environmental hyperthermia on gastrin, somatostatin and motilin in rat ulcerated antral mucosa. METHODS: Forty-two Wistar rats were equally divided into six groups, according to the room temperature (high and normal) and the treatment (acetic acid, normal saline and no treatment). Levels of gastrin, somatostatin and motilin in rat ulcerated antral mucosa were measured with a radioimmunoassay method. RESULTS: The average temperature and humidity were 32.5 degrees and 66.7% for the high temperature group, and 21.1 degrees and 49.3% for the normal temperature group, respectively. Gastric ulcer model was successfully induced in rat injected with 0.05 mL acetic acid into the antrum. In rats with gastric ulcers, the levels of gastrin and motilin increased, whereas the somatostatin level declined in antral mucosa, compared with those in rats treated with normal saline and the controls. However, the change extent in the levels of gastrin, motilin and somatostatin in antral mucosa was less in the high temperature group than in the normal temperature group. CONCLUSION: The levels of gastrin, somatostatin and motilin in rat ulcerated antral mucosal tissue remain relatively stable in a high temperature environment, which may relate to the equilibration of the dynamic system. |
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Authors:
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Feng-Peng Sun; Yu-Gang Song |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 10 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2004 Dec |
Date Detail:
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Created Date: 2004-11-04 Completed Date: 2005-01-05 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 3528-30 Citation Subset: IM |
Affiliation:
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Department of Gastroenterology, Nanfang Hospital, First Military medical University, Guangzhou 510515, Guangdong Province, China. phd@china.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adaptation, Physiological Animals Environment Fever / complications, metabolism* Gastric Mucosa / metabolism Gastrins / metabolism* Hot Temperature Male Motilin / metabolism* Pyloric Antrum / metabolism Rats Rats, Wistar Somatostatin / metabolism* Stomach Ulcer / complications, metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Gastrins; 51110-01-1/Somatostatin; 52906-92-0/Motilin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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