| Effect of elevated dissolved carbon dioxide concentrations on growth of Corynebacterium glutamicum on D-glucose and L-lactate. | |
MedLine Citation:
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PMID: 17275119 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of increased dissolved carbon dioxide concentrations on growth of Corynebacterium glutamicum was studied with continuous turbidostatic cultures. The carbon sources were either l-lactate or d-glucose. To increase the dissolved carbon dioxide concentration the carbon dioxide partial pressure of the inlet gas stream pCO2,IN was increased stepwise from 0.0003 bar (air) up to 0.79 bar, while the oxygen partial pressure of the inlet gas stream was kept constant at 0.21 bar. For each resulting carbon dioxide partial pressure pCO2 the maximum specific growth rate mu(max) was determined from the feed rate resulting from the turbidostatic control. On d-glucose and pCO2 up to 0.26 bar, mu(max) was mostly constant around 0.58 h(-1). Higher pCO2 led to a slight decrease of mu(max). On l-lactate mu(max) increased gradually with increasing carbon dioxide partial pressures from 0.37 h(-1) under aeration with air to a maximum value of 0.47 h(-1) at a pCO2 of 0.26 bar. At very high pCO2 (0.81 bar) mu(max) decreased down to 0.35 h(-1) independent of the carbon source. |
Authors:
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Carsten Bäumchen; Arnd Knoll; Bernward Husemann; Juri Seletzky; Bernd Maier; Carsten Dietrich; Ghassem Amoabediny; Jochen Büchs |
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Publication Detail:
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Type: Journal Article Date: 2007-01-10 |
Journal Detail:
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Title: Journal of biotechnology Volume: 128 ISSN: 0168-1656 ISO Abbreviation: J. Biotechnol. Publication Date: 2007 Mar |
Date Detail:
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Created Date: 2007-03-09 Completed Date: 2007-05-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8411927 Medline TA: J Biotechnol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 868-74 Citation Subset: IM |
Affiliation:
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Biochemical Engineering, RWTH Aachen University, D-52074 Aachen, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Carbon Dioxide
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pharmacology* Corynebacterium glutamicum / drug effects*, growth & development, metabolism Fermentation Glucose / metabolism Lactic Acid / metabolism Partial Pressure |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide; 50-21-5/Lactic Acid; 50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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