| Effect of ectopic pituitary homograft on the physiological status of rat testis. | |
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MedLine Citation:
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PMID: 3954089 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pituitary glands grafted under the kidney capsule provide a continuous supply of prolactin due to the absence of hypothalamic inhibitory factor. Increase in the level of prolactin in the rat may affect availability of hormone for reproductive function. Single pituitaries were transplanted under the kidney capsule of male rats. After six weeks of the transplant, the recipient rats were sacrificed and trophic activity of testosterone and intratesticular functions were assessed. The weights of ventral prostate and seminal vesicles, full and empty, showed significant increase from the control value. The activity of beta-glucuronidase in kidney, an androgen inducible enzyme, also increased in comparison with the control value. Incorporation of 32P in the nucleic acid fraction showed an increase. The increased rate of testosterone production and an alteration in spermatogenesis was associated with increased activity of acid phosphatase and decreased activity of beta-glucuronidase. The active mediation of lysosomal enzyme in testicular function as altered by prolactin was indicated. |
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Authors:
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P P Mathur; S Chattopadhyay |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Andrologia Volume: 18 ISSN: 0303-4569 ISO Abbreviation: Andrologia Publication Date: 1986 Jan-Feb |
Date Detail:
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Created Date: 1986-03-28 Completed Date: 1986-03-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0423506 Medline TA: Andrologia Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 84-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acid Phosphatase
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analysis Animals Ascorbic Acid / analysis Body Weight Glucuronidase / analysis Male Organ Size Phosphates / metabolism Pituitary Gland / transplantation* Rats Testis / physiology* Transplantation, Homologous |
| Chemical | |
Reg. No./Substance:
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0/Phosphates; 50-81-7/Ascorbic Acid; EC 3.1.3.2/Acid Phosphatase; EC 3.2.1.31/Glucuronidase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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