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Effect of early postnatal neutropenia in very low birth weight infants born to mothers with pregnancy-induced hypertension.
MedLine Citation:
PMID:  23300501     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
PURPOSE: In this study, we aimed to investigate the perinatal clinical conditions of very low birth weight (VLBW) infants born to mothers with pregnancy-induced hypertension (PIH) focusing on the effects of early postnatal neutropenia.
METHODS: We reviewed the medical records of 191 VLBW infants who were born at Konyang University Hospital, between March 2003 and May 2011. We retrospectively analyzed the clinical characteristics of the infants and their mothers and compared the incidence of perinatal diseases and mortality of the infants according to the presence or absence of maternal PIH and neutropenia on the first postnatal day.
RESULTS: Infants born to mothers with PIH showed an increased incidence of neutropenia on the first postnatal day (47.4%), cesarean delivery, and intrauterine growth restriction. When the infants born to mothers with PIH showed neutropenia on the first postnatal day, their incidence of respiratory distress syndrome (RDS) was increased (P=0.031); however, the difference was not found to be significant through logistic regression analysis. In all the VLBW infants, neutropenia on the first postnatal day was correlated with the development of RDS. The incidence of the other perinatal diseases involving sepsis and mortality did not significantly differ according to the presence or absence of neutropenia in infants born to mothers with PIH.
CONCLUSION: In VLBW infants born to mothers with PIH, the incidence of neutropenia on the first postnatal day was increased and it was not significantly correlated with the development of perinatal diseases involving RDS, sepsis, and mortality.
Authors:
Yang Hee Park; Gyung Min Lee; Jung Min Yoon; Enn Jung Cheon; Kyung Ok Ko; Yung Hyuk Lee; Jae Woo Lim
Publication Detail:
Type:  Journal Article     Date:  2012-12-20
Journal Detail:
Title:  Korean journal of pediatrics     Volume:  55     ISSN:  1738-1061     ISO Abbreviation:  Korean J Pediatr     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2013-01-09     Completed Date:  2013-01-10     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  101215374     Medline TA:  Korean J Pediatr     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  462-9     Citation Subset:  -    
Affiliation:
Department of Pediatrics, Konyang University College of Medicine, Daejeon, Korea.
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