| Effect of discrete brain lesions on hypothalamic and pituitary immunoreactive dynorphin. | |
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MedLine Citation:
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PMID: 2871529 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Radiofrequency lesions of the anterior hypothalamic area reduced immunoreactive dynorphin (ir-DYN) in the hypothalamus and in the neurointermediate lobe of the pituitary. Ablation of the medial preoptic area was not associated with any significant modification of ir-DYN in the tissue examined. Destruction of the medial basal hypothalamus in parallel lowered ir-DYN in the hypothalamus and in both pituitary lobes. Neonatal administration of monosodium glutamate had no significant effect on ir-DYN. These findings indicate that changes of ir-DYN in the hypothalamus and pituitary are associated with the destruction of anatomically and functionally distinct neural systems. |
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Authors:
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S Spampinato; S Stanzani; S Ferri |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Neuroscience letters Volume: 65 ISSN: 0304-3940 ISO Abbreviation: Neurosci. Lett. Publication Date: 1986 Mar |
Date Detail:
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Created Date: 1986-06-09 Completed Date: 1986-06-09 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7600130 Medline TA: Neurosci Lett Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 109-13 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anterior Hypothalamic Nucleus / physiology Dynorphins / analysis* Hypothalamus / analysis* Hypothalamus, Middle / physiology Male Pituitary Gland, Posterior / analysis* Preoptic Area / physiology Rats Rats, Inbred Strains |
| Chemical | |
Reg. No./Substance:
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74913-18-1/Dynorphins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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