Document Detail

Effect of direct-current countershocks on regional myocardial contractility and perfusion. Experimental studies.
MedLine Citation:
PMID:  7449055     Owner:  NLM     Status:  MEDLINE    
Very high energy electrical countershocks can cause morphologic damage to the myocardium. In this study we searched for functional correlates of these shock-induced morphologic changes. We used ultrasonic sonomicrometers to measure myocardial contractility and radiolabeled microspheres to assess perfusion. Acute and chronic experiments were conducted in 45 dogs, assessing the effect of both direct (epicardial) and transthoracic shocks on beating and fibrillating hearts. High-energy or rapidly repeated epicardial shocks caused subepicardial contraction abnormalities. This indicates that electrical current delivered to the myocardium in sufficiently high amounts and concentration can cause functional damage. Thus, in open-chest defibrillation during cardiac surgery, low energies (10-20 J) should be used initially and higher energies resorted to only if lower-energy shocks fail. However, single and multiple transthoracic shocks up to 460 J delivered energy caused no detectable contraction abnormalities. Myocardial perfusion did not fall after shocks. Thus, high-energy transthoracic shocks may have no deleterious effects on the contraction and perfusion of normal myocardium.
R E Kerber; J B Martins; J A Gascho; M L Marcus; J Grayzel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Circulation     Volume:  63     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1981 Feb 
Date Detail:
Created Date:  1981-03-17     Completed Date:  1981-03-17     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  323-32     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Pressure
Electric Countershock*
Heart Rate
Myocardial Contraction*
Ventricular Fibrillation / etiology
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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