Document Detail


Effect of dietary supplementation of probiotic and vitamin C on the immune response of Indian major carp, Labeo rohita (Ham.).
MedLine Citation:
PMID:  17434319     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The immunostimulatory effect of probiotics and vitamin C has been established in many systems including fish. An investigation was carried out to study the effect of dietary supplementation of a probiotic bacterium "Bacillus subtilis", vitamin C in the form of ascorbyl polyphosphate and their combination on the immune response of Indian major carp, rohu, (Labeo rohita Ham.) fingerlings fed for a period of 60 days. The total serum protein and globulin content was significantly higher (p<0.05) in probiotic (B. subtilis @ 10(8) CFU/g of the feed) fed group while the respiratory burst activity of blood neutrophils was significantly high in vitamin C (ascorbyl polyphosphate @100 mg per kg diet) fed group. The antibody level was significantly high in Bacillus subtilis treated group followed by the probiotic (B. subtilis @ 10(8) CFU/g of the feed) and ascorbyl polyphosphate (ascorbyl polyphosphate @100 mg per kg diet) combined group. The least percentage of mortality was recorded in B. subtilis treated group (25%) followed by 35 and 40% in ascorbyl polyphosphate treated and B. subtilis and ascorbyl polyphosphate combined groups, respectively.
Authors:
S K Nayak; P Swain; S C Mukherjee
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article     Date:  2007-03-07
Journal Detail:
Title:  Fish & shellfish immunology     Volume:  23     ISSN:  1050-4648     ISO Abbreviation:  Fish Shellfish Immunol.     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-08-13     Completed Date:  2008-09-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9505220     Medline TA:  Fish Shellfish Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  892-6     Citation Subset:  IM    
Affiliation:
Central Institute of Freshwater Aquaculture, Fish Health Management Division, Kausalyaganga 751002, Bhubaneswar, Orissa, India.
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MeSH Terms
Descriptor/Qualifier:
Animals
Antibodies, Bacterial / blood
Antioxidants / pharmacology*
Ascorbic Acid / pharmacology*
Bacillus subtilis / immunology
Bacterial Proteins / immunology
Bacterial Vaccines / immunology
Blood Proteins / analysis
Carps / immunology*
Dietary Supplements*
Edwardsiella tarda / chemistry,  immunology
Enterobacteriaceae Infections / immunology,  mortality,  veterinary*
Fish Diseases / immunology*,  microbiology,  mortality
Neutrophils / drug effects
Probiotics* / administration & dosage
Respiratory Burst / drug effects
Time Factors
Chemical
Reg. No./Substance:
0/Antibodies, Bacterial; 0/Antioxidants; 0/Bacterial Proteins; 0/Bacterial Vaccines; 0/Blood Proteins; 50-81-7/Ascorbic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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