| Effect of a dietary supplement combination on weight management, adipose tissue, cholesterol and triglycerides in obese subjects. | |
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MedLine Citation:
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PMID: 15377061 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A combination dietary supplement containing vitamins, minerals, herbs, fibers and amino acids was studied to determine its safety and efficacy on weight/ fat loss, cholesterol and triglycerides in a double-blind, placebo-controlled trail. Total body weight, body fat %, waist and hip measurements, total cholesterol and triglycerides were evaluated before and after 6 weeks treatment with combination supplement or placebo. The study population consisted in 27 mildly to moderately obese, otherwise healthy, volunteers. After 6 weeks of treatment, the combination supplement had a statistically significant (p<0.001, mu=0.05) positive weight reducing effect (-8.59Lb vs. +2.14 Lb). This weight reduction was associated with a corresponding statistically significant (p<0.001, mu=0.05) decrease in body fat % in the treatment group (-2.88%) vs. the placebo (+0.86%). In addition, significant decreases in total cholesterol (-22.94 mg/dL) and triglycerides (-39.29 mg/dL) were obtained plus reductions in waist and hip measurements. These positive results lead us to conclude, that the combination supplement studied herein is a safe and effective way to assist in weight/fat reduction and decreases in total cholesterol and triglycerides in relatively short time (6 weeks). |
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Authors:
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Michael J González; Jorge R Miranda-Massari; Carlos M Ricart |
Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Puerto Rico health sciences journal Volume: 23 ISSN: 0738-0658 ISO Abbreviation: P R Health Sci J Publication Date: 2004 Jun |
Date Detail:
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Created Date: 2004-09-20 Completed Date: 2004-10-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8303541 Medline TA: P R Health Sci J Country: Puerto Rico |
Other Details:
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Languages: eng Pagination: 121-4 Citation Subset: IM |
Affiliation:
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InBioMed Project, University of Puerto Rico, Medical Sciences Campus. mgonzalez@rcm.upr.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adipose Tissue
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drug effects* Adult Anthropometry Anti-Obesity Agents / therapeutic use* Cholesterol / blood* Dietary Supplements* Double-Blind Method Humans Male Middle Aged Obesity / blood, diet therapy* Triglycerides / blood* Weight Loss / physiology |
| Chemical | |
Reg. No./Substance:
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0/Anti-Obesity Agents; 0/Triglycerides; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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