Document Detail

Effect of dietary conjugated linoleic acid and monounsaturated fatty acid content on pig muscle and adipose tissue lipase and esterase activity.
MedLine Citation:
PMID:  17117816     Owner:  NLM     Status:  MEDLINE    
Three levels (0%, 1%, and 2%) of conjugated linoleic acid (CLA) were combined with two levels (low and high) of monounsaturated fatty acids (MUFA) for pig feeding. The activity of neutral lipase (NL), acid lipase (AL), phospholipase (PL), neutral esterase (NE), and acid esterase (AE) was measured in extracts from muscle and subcutaneous adipose tissues. The addition of CLA in the diet only affected the lipolytic activity in muscle, whereas differences in MUFA content of pig diets were mainly responsible for the lipolytic enzyme modifications observed in adipose tissue. Nevertheless, a significant effect of the interaction CLA x MUFA on the activity of several lipolytic enzymes was observed in both tissues. The effect of either linoleic acid (LA) or CLA on the activity of muscle and adipose lipolytic enzymes was determined by in vitro assays. Remarkable inhibitory or activation effects were detected depending on the enzyme and kind of tissue.
Diana Martín; Jorge Ruiz; Mónica Flores; Fidel Toldra
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  54     ISSN:  0021-8561     ISO Abbreviation:  J. Agric. Food Chem.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-11-22     Completed Date:  2007-01-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  9241-7     Citation Subset:  IM    
Food Science, Facultad de Veterinaria, Universidad de Extremadura, Avda. Universidad s/n, 10071 Cáceres, Spain.
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MeSH Terms
Adipose Tissue / enzymology,  metabolism
Animal Feed*
Esterases / analysis*
Fatty Acids / analysis,  metabolism*
Linoleic Acids, Conjugated / analysis,  metabolism*
Muscle, Skeletal / enzymology,  metabolism
Reg. No./Substance:
0/Fatty Acids; 0/Linoleic Acids, Conjugated; EC 3.1.-/Esterases

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