Document Detail

Effect of dichloromethylene diphosphonate on fluoride balance in healthy men.
MedLine Citation:
PMID:  6221038     Owner:  NLM     Status:  MEDLINE    
Healthy men with a daily intake of 0.37 mg fluoride were given dichloromethylene diphosphonate (Cl2MDP) or a placebo during a period of ambulation followed by bed rest. In both groups, serum ionic fluoride was unchanged, and fluoride balances were negative, but Cl2MDP significantly reduced loss of fluoride in the treated groups.
U R Maheshwari; L Leybin; J T McDonald; V S Schneider; E Newbrun; H C Hodge
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of dental research     Volume:  62     ISSN:  0022-0345     ISO Abbreviation:  J. Dent. Res.     Publication Date:  1983 May 
Date Detail:
Created Date:  1983-06-10     Completed Date:  1983-06-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0354343     Medline TA:  J Dent Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  559-61     Citation Subset:  D; IM; S    
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MeSH Terms
Bed Rest
Clodronic Acid / pharmacology*
Diphosphonates / pharmacology*
Double-Blind Method
Fluorides / analysis,  metabolism*
Reg. No./Substance:
0/Diphosphonates; 0/Fluorides; 0/Placebos; 10596-23-3/Clodronic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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