Document Detail

Effect of diazepam on food consumption in rats.
MedLine Citation:
PMID:  415319     Owner:  NLM     Status:  MEDLINE    
Diazepam significantly increased milk consumption in rats that had never been exposed to this food before but not in rats trained to drink milk. Diazepam failed to increase lever-pressing for food reward except when this behavior had been previously suppressed by the simultaneous administration of electric shock. These data suggest that diazepam does not alter appetite, but enhances the expression of motivation suppressed by instinct or training.
D N Johnson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Psychopharmacology     Volume:  56     ISSN:  0033-3158     ISO Abbreviation:  Psychopharmacology (Berl.)     Publication Date:  1978 Jan 
Date Detail:
Created Date:  1978-04-17     Completed Date:  1978-04-17     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7608025     Medline TA:  Psychopharmacology (Berl)     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  111-2     Citation Subset:  IM    
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MeSH Terms
Conditioning, Operant / drug effects
Diazepam / pharmacology*
Feeding Behavior / drug effects
Reg. No./Substance:

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